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Updated: Dec 24, 2025

Synthesis and Calibration of Phosphorescent Nanoprobes for Oxygen Imaging in Biological Systems
Published on: March 3, 2010
A cell-membrane-permeable europium complex as an efficient luminescent probe for singlet oxygen
Zhichao Dai1, Lu Tian, Yunna Xiao
1State Key Laboratory of Fine Chemicals, School of Chemistry, Dalian University of Technology, Dalian 116024, China. zhiqiangye2001@yahoo.com.cn jingliyuan@yahoo.com.cn.
Abstract:
A unique cell-membrane-permeable europium complex has been developed as a probe for time-gated luminescence detection of singlet oxygen (1O2). Combined with the time-gated luminescence imaging technique, the probe was successfully used for investigating the time-dependent generation and distribution of 1O2 induced by the clinical drugs of photodynamic therapy in cancer cells.
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