Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Isolation and characterization of microsatellites in Rattus rattus.

Molecular ecology resources·2011
Same author

Range-wide population genetic structure of the European bitterling (Rhodeus amarus) based on microsatellite and mitochondrial DNA analysis.

Molecular ecology·2010
Same author

Plio-Pleistocene history of West African Sudanian savanna and the phylogeography of the Praomys daltoni complex (Rodentia): the environment/geography/genetic interplay.

Molecular ecology·2010
Same author

Comparative phylogeography of two sibling species of forest-dwelling rodent (Praomys rostratus and P. tullbergi) in West Africa: different reactions to past forest fragmentation.

Molecular ecology·2009
Same author

Transplantation of porcine umbilical cord matrix cells into the rat brain.

Experimental neurology·2003
Same author

Incorporation of bovine bone marrow stromal cells into porcine foetal tissues after xenotransplantation.

Anatomia, histologia, embryologia·2003

Related Experiment Video

Updated: Dec 24, 2025

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles
08:26

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Published on: October 19, 2015

12.5K

Hexagonal magnetite nanoprisms: preparation, characterization and cellular uptake.

H Wang1, T B Shrestha, M T Basel

  • 1Kansas State University, Department of Chemistry, 201 CBC Building, Manhattan, KS 66506, USA. hongwang@ksu.edu sbossman@ksu.edu.

Journal of Materials Chemistry. B
|April 9, 2020
PubMed
Summary

Researchers developed low-toxicity hexagonal iron oxide (Fe3O4) nanoplatelets for magnetic hyperthermia cancer therapy. These nanoparticles exhibit high heat generation efficiency and minimal cellular toxicity, paving the way for new cancer treatment strategies.

More Related Videos

Using Magnetometry to Monitor Cellular Incorporation and Subsequent Biodegradation of Chemically Synthetized Iron Oxide Nanoparticles
08:13

Using Magnetometry to Monitor Cellular Incorporation and Subsequent Biodegradation of Chemically Synthetized Iron Oxide Nanoparticles

Published on: February 27, 2021

5.0K
Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
10:23

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Published on: December 13, 2016

10.3K

Related Experiment Videos

Last Updated: Dec 24, 2025

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles
08:26

Cell Labeling and Targeting with Superparamagnetic Iron Oxide Nanoparticles

Published on: October 19, 2015

12.5K
Using Magnetometry to Monitor Cellular Incorporation and Subsequent Biodegradation of Chemically Synthetized Iron Oxide Nanoparticles
08:13

Using Magnetometry to Monitor Cellular Incorporation and Subsequent Biodegradation of Chemically Synthetized Iron Oxide Nanoparticles

Published on: February 27, 2021

5.0K
Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells
10:23

Synthesis of Cationized Magnetoferritin for Ultra-fast Magnetization of Cells

Published on: December 13, 2016

10.3K

Area of Science:

  • Nanotechnology
  • Biomedical Engineering
  • Materials Science

Background:

  • Magnetic hyperthermia relies on iron oxide nanocrystals' ability to generate heat under an alternating magnetic field (AMF).
  • Previous research has synthesized various iron oxide nanostructures, but hexagonal Fe3O4 prisms with low toxicity have been challenging to produce.

Purpose of the Study:

  • To synthesize hexagonal Fe3O4 nanoplatelets with controlled dimensions and low toxicity.
  • To evaluate their potential for AMF hyperthermia and cell-based cancer targeting.

Main Methods:

  • Utilized a dual ligand system under feasible reaction conditions to synthesize hexagonal Fe3O4 nanoplatelets (45 ± 5 nm edge length, 5–6 nm thickness).
  • Coated the Fe3O4 hexagons with a dopamine-based ligand to enhance aqueous dispersibility.
  • Assessed the Specific Absorption Rate (SAR) and cytotoxicity against RAW264.7 cells.

Main Results:

  • Successfully synthesized nearly perfect hexagonal Fe3O4 nanoplatelets.
  • Achieved a high Specific Absorption Rate (SAR) of >750 W g(Fe)⁻¹.
  • Demonstrated minimal toxicity to RAW264.7 cells.

Conclusions:

  • Developed a novel method for producing low-toxicity hexagonal Fe3O4 nanoplatelets.
  • These nanoparticles show significant potential for AMF hyperthermia cancer therapy due to their high SAR and biocompatibility.
  • The findings support their application in cell-based cancer targeting strategies.