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Polymeric multifunctional nanomaterials for theranostics.

Haisheng Peng1, Xiaoying Liu, Guangtian Wang

  • 1Department of Chemical and Biological Engineering, Iowa State University, 2114 Sweeney Hall, Ames, IA 50011, USA. qunwang@iastate.edu.

Journal of Materials Chemistry. B
|April 9, 2020
PubMed
Summary

Polymeric multifunctional nanomaterials integrate therapy and diagnostics for synergistic theranostics. These advanced nanocarriers deliver drugs and imaging agents, enabling simultaneous diagnosis and treatment with enhanced properties.

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Area of Science:

  • Biomaterials Science
  • Nanotechnology
  • Medical Diagnostics and Therapeutics

Background:

  • Nanocarriers are emerging platforms for integrating therapy and diagnostics.
  • Theranostic nanomaterials combine therapeutic agents and imaging components for synergistic diagnosis and treatment.

Purpose of the Study:

  • To review and compare polymeric materials for manufacturing theranostic nanomaterials.
  • To highlight recent advancements in polymeric multifunctional nanomaterials for synergistic theranostics.

Main Methods:

  • Discussion and comparison of polymeric materials for theranostic nanocarrier fabrication.
  • Review of methods for encapsulating/conjugating drugs and imaging agents onto nanocarriers.
  • Analysis of incorporating magnetic, electrical, and optical properties via imaging agents.

Main Results:

  • Polymeric multifunctional nanomaterials can encapsulate drugs and imaging agents.
  • These nanomaterials exhibit magnetic, electrical, and optical properties for imaging.
  • Various imaging agents like quantum dots and magnetic nanoparticles are incorporated.

Conclusions:

  • Polymeric multifunctional nanomaterials offer significant advantages for theranostic applications.
  • These materials enable simultaneous diagnosis and therapy with synergistic effects.
  • The review provides a comprehensive overview of the state-of-the-art in polymeric theranostics.