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Updated: Dec 24, 2025

Synthesis of Immunotargeted Magneto-plasmonic Nanoclusters
Published on: August 22, 2014
Facile synthesis of magnetic core-shell nanocomposites for MRI and CT bimodal imaging
Jing Zhu1, Jiaqing Wang, Xin Wang
1Key Laboratory of Organic Synthesis of Jiangsu Province, College of Chemistry, Chemical Engineering and Materials Science & Collaborative Innovation Center of Suzhou Nano Science and Technology, Soochow University, Suzhou, 215123, China. hongwei@suda.edu.cn panyue@suda.edu.cn.
Abstract:
With the development of nanotechnology, nanocomposites have been used as bimodal contrast agents for magnetic resonance (MR) and computed tomography (CT) imaging. We have developed a facile method for the synthesis of iron oxide@bismuth sulfide magnetic core-shell nanocomposites. These bifunctional nanocomposites can be made water-soluble via PEG coating and present strong MRI/CT contrast enhancement. Evaluation of cytotoxicity by MTT assay shows that the nanocomposites have low cytotoxicity. The results illustrate that the nanocomposites have great potential as bimodal imaging agents for MR/CT.
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