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Updated: Dec 24, 2025

Development and Functionalization of Electrolyte-Gated Graphene Field-Effect Transistor for Biomarker Detection

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Published on: February 1, 2022

pH-induced on/off-switchable graphene bioelectronics.

Onur Parlak¹, Anthony P F Turner, Ashutosh Tiwari

¹Biosensors and Bioelectronics Centre, IFM, Linköping University, S-58183 Linköping, Sweden. ashutosh.tiwari@liu.se.

Journal of Materials Chemistry. B

|April 9, 2020

Summary

This summary is machine-generated.

Researchers developed pH-responsive graphene interfaces for bioelectronics. These switchable interfaces enable on-demand, specific biosensor operation, advancing analytical applications.

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Area of Science:

Materials Science
Bioelectronics
Analytical Chemistry

Background:

Switchable interfaces offer reversible reactivity with analytes.
This enables response to biomolecular activity via stimuli.
Graphene is a promising material for advanced interfaces.

Purpose of the Study:

To design and demonstrate stimuli-responsive graphene interfaces for pH-encoded bioelectronics.
To enable on-demand and specific operation of biosensors.
To explore potential applications in analytical sciences.

Main Methods:

Fabrication of stimuli-responsive graphene interfaces.
Integration of interfaces into bioelectronic systems.
Testing interface response to pH variations and biomolecules.

Main Results:

Demonstrated successful pH-encoded operation of bioelectronic devices.
Achieved highly specific and reversible interface switching.
Confirmed the ability to detect biomolecular activity.

Conclusions:

Stimuli-responsive graphene interfaces provide a novel platform for bioelectronics.
These interfaces facilitate on-demand, specific biosensing.
Significant potential for diverse analytical applications is highlighted.