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A signal-accumulating DNAzyme-crosslinked hydrogel for colorimetric sensing of hydrogen peroxide
Haixu Zhao1, Gangfeng Jiang, Jinpeng Weng
1Key Laboratory of Structure-Based Drugs Design & Discovery (Shenyang Pharmaceutical University) of Ministry of Education, School of Pharmaceutical Engineering, Shenyang Pharmaceutical University, Shenyang 110016, P. R. China. mz_liu03@163.com.
Abstract:
A signal-accumulating DNAzyme-crosslinked hydrogel was designed and prepared for colorimetric sensing of hydrogen peroxide. In this hydrogel-based sensing system, sensing signal molecules were effectively accumulated inside the gel and the concentrated DNAzyme inside the gel remarkably increased the catalytic activity, resulting in a rapid and highly sensitive detection of hydrogen peroxide.
