Related Experiment Video
Updated: Dec 24, 2025

An Aptamer-based Sensor for Unchelated GadoliniumIII
Published on: January 9, 2017
The application of a G-quadruplex based assay with an iridium(iii) complex to arsenic ion detection and its
Sheng Lin1, Wanhe Wang, Chong Hu
1Department of Chemistry, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China. edmondma@hkbu.edu.hk kangningren@hkbu.edu.hk.
Abstract:
In this work, the iridium(iii) complex 1 was synthesized and employed in constructing an assay which is based on a G-quadruplex for detecting arsenic ions in aqueous solution. The assay achieved a detection limit of 7.6 nM (ca. 0.57 μg L-1) and showed high selectivity towards arsenic ions over other metal ions. Additionally, the assay could function in natural water and a simple microfluidic chip was used to investigate the potential of this platform for real-time detection.

