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Updated: Dec 24, 2025
A Bright NIR-II Fluorescence Probe for Vascular and Tumor Imaging
Published on: March 17, 2023
In situ synthesis of NIR-light emitting carbon dots derived from spinach for bio-imaging applications
Liping Li1, Ruiping Zhang, Chunxiang Lu
1National Engineering Laboratory for Carbon Fiber Technology, Institute of Coal Chemistry, Chinese Academy of Sciences, Taiyuan 030001, P. R. China. chunxl@sxicc.ac.cn liuyd@sxicc.ac.cn.
Abstract:
Near infrared (NIR)-light emitting fluorescent probes have attracted extensive research attention in the bioimaging field due to their deep tissue penetration, minimal auto-fluorescence and lower emission light damage to bio-tissues. Herein, we designed and prepared NIR-light emitting CDs (R-CDs) from spinach by a one-step solvothermal method. The R-CDs exhibited good water solubility, a maximum fluorescence emission peak at 680 nm, a high quantum yield of 15.34%, remarkable photo-stability and resistance to metal ions in a body-simulating environment, excellent compatibility, negligible toxicity, and superior labelling capability in vitro and in vivo. These findings significantly highlight the design of NIR-light emitting CDs and exploit their bio-imaging applications.
