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Synthesis of Functionalized 10-nm Polymer-coated Gold Particles for Endothelium Targeting and Drug Delivery
Published on: January 15, 2018
Synergistic and targeted drug delivery based on nano-CeO2 capped with galactose functionalized pillar[5]arene via
Xiaowen Wu1, Ying Zhang, Yuchao Lu
1Shaanxi Key Laboratory of Natural Products & Chemical Biology, College of Chemistry and Pharmacy, Northwest A&F University, Yangling, 712100 Shaanxi, P. R. China. peiyx@nwafu.edu.cn peizc@nwafu.edu.cn.
Abstract:
A smart drug delivery system based on porous CeO2 nano-rods (CeONRs) capped with galactose functionalized pillar[5]arene via host-guest interactions has been constructed, which showed GSH-responsiveness, synergism with anticancer drugs and cancer targeting ability resulting from its disulphide unit, ceria properties and galactose units, respectively.
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