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Colloids

Colloids

Children at play often make suspensions such as mixtures of mud and water, flour and water, or a suspension of solid pigments in water known as tempera paint. These suspensions are heterogeneous mixtures composed of relatively large particles that are visible to the naked eye or can be seen with a magnifying glass. They are cloudy, and the suspended particles settle out after mixing. On the other hand, a solution is a homogeneous mixture in which no settling occurs and in which the dissolved...

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Updated: Dec 24, 2025

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film

Automated Lipid Bilayer Membrane Formation Using a Polydimethylsiloxane Thin Film

Published on: July 10, 2016

Spreading-induced dewetting for monolayer colloidosomes with responsive permeability.

Leyan Lei¹, Xin Tang, Pingan Zhu

¹Department of Mechanical Engineering, University of Hong Kong, Hong Kong.

Journal of Materials Chemistry. B

|April 9, 2020

Summary

Researchers developed a novel method to create smart monolayer colloidosomes using spreading-induced dewetting of Pickering emulsion droplets. These versatile capsules offer controlled release for active ingredients, particularly in biological applications.

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Last Updated: Dec 24, 2025

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Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Temperature-Controlled Assembly and Characterization of a Droplet Interface Bilayer

Published on: April 19, 2021

Area of Science:

Materials Science
Colloid and Surface Chemistry
Chemical Engineering

Background:

Pickering emulsions, stabilized by solid particles, are crucial in various applications.
Fabricating precise colloidal structures like colloidosomes remains a challenge.
Controlling shell properties is key for advanced encapsulation and delivery systems.

Purpose of the Study:

To develop a novel method for fabricating monolayer colloidosomes.
To investigate the spreading-induced dewetting mechanism of Pickering emulsion droplets.
To create smart, tunable colloidosomes for encapsulation and controlled release.

Main Methods:

Utilized a spreading-induced dewetting approach for water-in-oil-in-water (W/O/W) double emulsion droplets.
Employed a microfluidic-templated strategy for precise structure formation.
Incorporated thermo-responsive copolymers for tunable surface properties.

Main Results:

Successfully fabricated highly monodisperse monolayer colloidosomes.
Demonstrated tunable permeability, biocompatibility, and mechanical stability.
Achieved high encapsulation efficiency for active ingredients.
The dewetting process was triggered by the spreading of a fluorinated oil phase on the water/air surface.

Conclusions:

The spreading-induced dewetting method offers a robust route to smart monolayer colloidosomes.
These colloidosomes exhibit desirable properties for effective encapsulation, transport, and release.
The developed technology holds significant potential for delivering biologically active materials.