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Self-assembled antibacterial coating by N-halamine polyelectrolytes on a cellulose substrate
Ying Liu1, Jing Li, Xiaoli Cheng
1Key Laboratory of Eco-Textiles of Ministry of Education, College of Textiles and Clothing, Jiangnan University, Wuxi 214122, Jiangsu, China. xhren@jiangnan.edu.cn.
Journal of Materials Chemistry. B
|April 9, 2020
Summary
This study developed antimicrobial cotton fabrics using N-halamine polymers. The coated fabrics effectively killed bacteria and showed no skin irritation, indicating potential for biomedical use.
Area of Science:
- Materials Science
- Polymer Chemistry
- Textile Science
Background:
- N-halamine compounds offer potent antimicrobial properties.
- Developing durable and safe antimicrobial textiles is crucial for various applications.
Purpose of the Study:
- To synthesize and apply N-halamine polymer precursors onto cotton fabrics.
- To evaluate the antimicrobial efficacy and safety of the coated fabrics.
Main Methods:
- Layer-by-layer (LbL) deposition of cationic (CHP) and anionic (AHP) N-halamine polymers.
- Characterization using SEM, XPS, and FTIR.
- Antimicrobial testing against Staphylococcus aureus and Escherichia coli.
- Chlorine retention and skin irritation tests.
Main Results:
- Successful synthesis and LbL coating of N-halamine polymers on cotton.
- Chlorinated fabrics (CHP-Cl, AHP-Cl) achieved 100% S. aureus and 99.73% E. coli inactivation.
- Over 51% chlorine retention after 50 washes.
- No skin irritation observed in rabbit tests.
Conclusions:
- LbL deposition is an effective method for creating antimicrobial N-halamine cotton fabrics.
- The developed fabrics exhibit excellent biocidal activity and durability.
- The non-irritating nature suggests potential for biomedical applications.

