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Updated: Dec 24, 2025
Confocal Time Lapse Imaging as an Efficient Method for the Cytocompatibility Evaluation of Dental Composites
Published on: November 9, 2014
Occupational exposure of dental technicians to methyl methacrylate: Genotoxicity assessment
Buğra Soykut1, Onur Erdem2, Can Özgür Yalçın3
1Gulhane Military Medical Academy, Department of Pharmaceutical Toxicology, 06010, Ankara, Turkey.
Abstract:
Dental technicians may be chronically exposed to methyl methacrylate (MMA), used in the production of dental prostheses. We have studied whether occupational exposure to MMA affects genotoxicity biomarkers such as 8-OHdG formation, comet assay, and buccal micronucleus frequency. MMA exposure was assessed via ambient air analysis. Although no significant differences between exposed and non-exposed individuals were seen with respect to blood genotoxicity measurements, we found a higher level of buccal-cell anomalies in the exposed group.
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