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Updated: Dec 24, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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A Ganoderma-Derived Compound Exerts Inhibitory Effect Through Formyl Peptide Receptor 2

Huirong Wang1,2, Xingrong Peng3, Yunjun Ge1

  • 1Institute of Chinese Medical Sciences, State Key Laboratory of Quality Research in Chinese Medicine, University of Macau, Macau, Macau.

Frontiers in Pharmacology
|April 9, 2020
PubMed
Summary

A compound from Ganoderma, C18, inhibits inflammation by targeting formyl peptide receptor 2 (FPR2). This discovery offers a potential new avenue for developing anti-inflammatory therapies.

Keywords:
Ganodermaanti-inflammatorychemotaxisfluorescence resonance energy transferformyl peptide receptorssuperoxide

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