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The relationship between serum zinc levels and myopia
Niamh Burke1, John S Butler1,2, Ian Flitcroft1,3
1Centre for Eye Research Ireland, School of Physics, Clinical and Optometric Sciences, College of Sciences and Health, Technological University Dublin , Dublin, Ireland.
Clinical & Experimental Optometry
|April 9, 2020
Summary
Serum zinc levels were not associated with myopia development in Korean adolescents. This study found no link between zinc status and myopia, suggesting diet may not be a key factor in its progression.
Area of Science:
- Ophthalmology
- Nutritional Science
- Public Health
Background:
- Myopia, a condition linked to eye growth, may be influenced by nutrition.
- Previous Asian studies indicated lower serum zinc in myopic children.
- This research investigated the serum zinc-myopia relationship in a Korean population.
Purpose of the Study:
- To determine if serum zinc levels correlate with myopia in adolescents.
- To analyze the association between zinc status and refractive error in young Koreans.
Main Methods:
- Utilized data from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010.
- Analyzed 304 participants aged 12–19 years.
- Measured serum zinc via ICP-MS and refractive error via non-cycloplegic autorefraction, with multivariate analysis.
Main Results:
- 84% of participants were myopic; no significant difference in serum zinc between myopic and non-myopic groups (p=0.81).
- Multivariate analysis showed no association between serum zinc and myopia after adjusting for covariates.
- No relationship was found between spherical equivalent refraction and serum zinc in myopic individuals (p=0.46).
Conclusions:
- No association was found between serum zinc and myopia in Korean adolescents (12-19 years).
- The study highlights the need for more sensitive biomarkers for zinc status in myopia research.
- Current findings suggest serum zinc may not be a significant factor in myopia development in this population.
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