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PRIRATE 2020 guidelines for reporting randomized trials in Endodontics: explanation and elaboration
V Nagendrababu1, H F Duncan2, L Bjørndal3
1Division of Clinical Dentistry, School of Dentistry, International Medical University, Kuala Lumpur, Malaysia.
International Endodontic Journal
|April 9, 2020
Summary
The Preferred Reporting Items for Randomized Trials in Endodontics (PRIRATE) 2020 guidelines improve the quality of endodontic research. Implementing PRIRATE 2020 enhances randomized clinical trial reporting and reduces bias.
Area of Science:
- Dental Research
- Clinical Trials
- Endodontics
Background:
- Randomized clinical trials (RCTs) are crucial for evaluating interventions in Endodontics.
- Current RCT reporting quality in Endodontics is suboptimal, potentially introducing bias.
- Existing reporting guidelines like CONSORT require adaptation for specialized fields.
Purpose of the Study:
- To introduce the Preferred Reporting Items for Randomized Trials in Endodontics (PRIRATE) 2020 guidelines.
- To provide detailed explanations and examples for implementing the PRIRATE 2020 checklist and flowchart.
- To improve the quality and reduce bias in published endodontic RCTs.
Main Methods:
- Development of PRIRATE 2020 guidelines through a consensus process.
- Integration and adaptation of the CONsolidated Standards of Reporting Trials (CONSORT) statement.
- Incorporation of Clinical and Laboratory Images in Publications (CLIP) principles.
Main Results:
- PRIRATE 2020 guidelines offer a standardized framework for reporting endodontic RCTs.
- The guidelines aim to minimize bias and enhance manuscript quality.
- An accompanying explanation and elaboration document is available for authors.
Conclusions:
- Full implementation of PRIRATE 2020 will elevate the standard of endodontic research reporting.
- Improved reporting facilitates better understanding and application of research findings.
- Adherence to PRIRATE 2020 is essential for robust clinical study design in Endodontics.
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