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Correlation between clinical risk factors and tracheal intubation difficulty in infants with Pierre-Robin syndrome: a

Yanli Liu1, Jiashuo Wang2, Shan Zhong3

  • 1Science and technology department, China Pharmaceutical University, Nanjing, People's Republic of China.

BMC Anesthesiology
|April 10, 2020
PubMed

Insights

Difficult tracheal intubation in infants with Pierre Robin syndrome (PRS) is linked to throat area size. Other factors like body surface area, weight, and gender also impact intubation difficulty.

Area of Science:

  • Anesthesiology
  • Pediatric Airway Management
  • Medical Imaging

Background:

  • Difficult tracheal intubation presents a significant challenge for anesthesiologists.
  • Pierre Robin syndrome (PRS) is associated with craniofacial abnormalities that can complicate airway management.
  • Computed tomography (CT) offers detailed anatomical visualization for pre-anesthetic assessment.

Purpose of the Study:

  • To evaluate the difficulty of tracheal intubation in infants diagnosed with Pierre Robin syndrome (PRS).
  • To utilize computed tomography (CT) imaging to aid in airway management strategies for these infants.
  • To identify clinical factors correlating with intubation difficulty in PRS patients.

Main Methods:

  • A retrospective analysis of clinical data and CT images from 96 infants with PRS was performed.
  • CT images underwent processing including color space conversion, binarization, contour acquisition, and area calculation.
  • Statistical analysis was conducted to determine correlations between clinical factors and intubation difficulty, and to compare risk factors.

Main Results:

  • A significant correlation (absolute coefficient value of 0.54) was found between throat area and tracheal intubation difficulty.
  • Body surface area, infant weight, and gender demonstrated statistically significant differences related to intubation difficulty.
  • These findings highlight specific anatomical and demographic factors influencing airway management challenges.

Conclusions:

  • Throat area is a significant predictor of tracheal intubation difficulty in infants with PRS.
  • Body surface area, weight, and gender are potential contributing factors to intubation difficulty in this population.
  • CT-guided assessment of airway dimensions can improve anesthetic management for infants with PRS.
Abstract

Keywords:
OpenCVPierre-Robin syndromeTracheal intubation anesthesia

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