Preparation of Injectable Composite Hydrogels by Blending Poloxamers with Calcium Carbonate-Crosslinked Sodium
Ningxia Xu1, Jing Xu1, Xiaoyan Zheng2
1School of Medicine Xi'an International University Xi'an 710077, Shaanxi China.
Chemistryopen
|April 10, 2020
Abstract:
The effects of calcium carbonate-crosslinked sodium alginate on poloxamer hydrogels have been investigated. The mechanical strength, degradability, and thermal stability of hydrogels were characterized. The chemical and physical crosslinking in the composite hydrogels has resulted in an improvement of the compressive strength and elasticity of the hydrogels. These mixed hydrogels showed improved mechanical properties, elasticity, and stability as well as environmental responsiveness and injectability.
