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[Microcirculation changes of three yin-meridians of hand in the forearm in rabbits with arrhythmia: a comparative
Chao Peng1, Yi Lin1, Shou-Qin Yang1
1College of Acupuncture-Moxibustion and Tuina, Beijing University of CM, Beijing 100029, China.
Objective:
To observe the microcirculation changes of three yin-meridians of hand in the forearm in rabbits with arrhythmia, and to compare the differences of responses among the three yin-meridians of hand.
Methods:
A total of 20 New Zealand rabbits were randomly divided into a saline group and a model group, 10 rabbits in each one. The rabbits were anesthetized with intravenous injection of 20% ethyl carbamate (3.3 mL/kg) at ear vein; the saline group was injected with 0.9% sodium chloride solution (1 mL/kg), while the model group was injected with 0.4% barium chloride solution (1 mL/kg) to establish the arrhythmia model. The microcirculation changes of the three yin-meridians of hand were observed and analyzed by laser speckle blood flow imaging technique before and after the intervention.
Results:
Compared before modeling, the microcirculation perfusion of the three yin-meridians of hand in the model group was significantly reduced (P<0.01), and the reduction in the jueyin meridian was more significant than that in the shaoyin meridian (P<0.05), but there was no significant difference between the taiyin meridian and shaoyin meridian (P>0.05). There was a negative correlation between microcirculation perfusion and position (P<0.001), indicating the closer to the elbow, the more the microcirculation perfusion decreased.
Conclusion:
During arrhythmia in rabbits, the dysfunction of qi and blood existes in the three yin-meridians of hand in the forearm, particularly the jueyin meridian. In addition, the closer to the elbow, the more obvious the reaction of the three yin-meridians of hand is.
