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Updated: Dec 24, 2025

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Laser Ablation and Intravital Microscopy to Study Intestinal Remodeling
Published on: June 9, 2023
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[Submucosal laser ablation of internal hemorrhoids]
A Yu Titov1, I V Kostarev1, L A Blagodarny2
1A.N. Ryzhikh State Scientific Center of Coloproctology of the Ministry of Health of Russia, Moscow, Russia.
Khirurgiia
|April 10, 2020
Summary
Submucosal laser ablation (SLT) effectively treats internal hemorrhoids grades 2-3 with high success rates. While generally safe, further research is needed to refine laser parameters and long-term outcomes for this hemorrhoid treatment.
Area of Science:
- Gastroenterology
- Minimally Invasive Surgery
- Laser Therapeutics
Background:
- Internal hemorrhoids affect a significant portion of the population.
- Current treatment options for internal hemorrhoids vary in efficacy and invasiveness.
- Submucosal laser ablation (SLT) presents a minimally invasive approach.
Purpose of the Study:
- To systematically review the efficacy and safety of submucosal laser ablation (SLT) for internal hemorrhoid treatment.
- To analyze outcomes based on available prospective clinical trial data.
Main Methods:
- Systematic review of 10 prospective clinical trials from PubMed, Cochrane Library, and Elibrary up to January 2019.
- Included studies focused on isolated SLT or SLT combined with other minimally invasive procedures.
- Data extraction on efficacy, safety, and complications associated with SLT.
Main Results:
- SLT is primarily used for hemorrhoids grades 2-3.
- Procedure efficacy ranged from 91.1-100% at 6 months and 87.5-100% at 12 months.
- Reported complications included bleeding (8.4%), edema (8.2%), urinary retention (1.2%), anal fistula (0.6%), and perianal abscess (0.14%).
Conclusions:
- Submucosal laser ablation is an effective and safe treatment for grades 2-3 internal hemorrhoids.
- Further research is necessary to establish clear guidelines for laser parameters and indications.
- Long-term outcome data is limited, warranting additional investigation.
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