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Updated: Oct 7, 2026

Robust Ligature-Induced Model of Murine Periodontitis for the Evaluation of Oral Neutrophils
Published on: January 21, 2020
Guest Editorial: Clarifications on the use of the new classification of periodontitis
Mariano Sanz1, Panos N Papapanou2, Maurizio S Tonetti3,4
1ETEP Research Group, Faculty of Dentistry, Complutense University of Madrid, Madrid, Spain.
Abstract:
This editorial provides clarifications on the application of the Stage and Grade classification of periodontitis. In particular it describes: (1) how to apply the extent criterion to the defined Stage of the disease; and (2) how to calculate tooth loss because of periodontitis in Stage III and IV cases presenting with evidently hopeless (irrational to treat) teeth with a clinical definition of such teeth.
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