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Related Concept Videos

Dysrhythmias II: Classification of Tachyarrhythmias01:28

Dysrhythmias II: Classification of Tachyarrhythmias

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Tachyarrhythmias are a type of dysrhythmia where the heart rate exceeds 100 beats per minute. Here are some common types of tachyarrhythmias:Sinus TachycardiaSinus tachycardia originates from increased impulses from the sinus node, leading to an elevated heart rate. It is often triggered by stress, fever, or exercise.Patients may experience palpitations, a sensation of a racing heart, dizziness, and chest discomfort.Causes and Risk Factors: Common causes include physical exertion, emotional...
384
ECG Interpretation of Arrhythmias I: Sinus Arrhythmias01:16

ECG Interpretation of Arrhythmias I: Sinus Arrhythmias

647
Arrhythmias are disturbances in the heart's rhythm that lead to abnormal heartbeats. These irregularities can originate from different parts of the heart and are classified based on their origin and nature.
Types of Arrhythmias
Sinus Node Arrhythmias
Sinus Bradycardia: Originating from the sinoatrial (SA) node, sinus bradycardia involves slower impulses, resulting in a heart rate of less than 60 beats per minute (bpm). Causes include sleep, vagal stimulation, beta-blockers, hypothyroidism,...
647
Disturbances in Heart Rhythm01:29

Disturbances in Heart Rhythm

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Arrhythmia or dysrhythmia refers to an abnormal heart rhythm caused by a defect in the heart's conduction system. It can cause the heart to beat irregularly, too quickly, or too slowly, leading to symptoms like chest pain, shortness of breath, and fainting. Factors such as stress, caffeine, alcohol, nicotine, cocaine, certain drugs, congenital defects, diseases, and electrolyte abnormalities can trigger arrhythmias.
Arrhythmias are categorized by their speed, rhythm, and origin. A slow heart...
2.3K
Increased pulse rate01:17

Increased pulse rate

973
Tachycardia is a condition marked by an abnormally fast or irregular heart rate, surpassing the typical resting rate. In adults, tachycardia is characterized by a pulse rate ranging from 100 to 180 beats per minute. The increased heart rate can result in inadequate blood flow to various body parts, ultimately diminishing the oxygen supply to organs and tissues.
Many factors can elevate the risk of developing tachycardia. These include advanced age, a family history of arrhythmias, and an...
973
Dysrhythmias IV: Characteristics of Bradyarrhythmias01:18

Dysrhythmias IV: Characteristics of Bradyarrhythmias

380
Bradyarrhythmias are cardiac rhythm disorders characterized by a slower-than-normal heart rate, typically defined as fewer than 60 beats per minute. Some of which are discussed here:Sinus BradycardiaSinus bradycardia presents a heart rate lower than 60 beats per minute, with a regular rhythm originating from the SA node. The ECG typically shows normal P waves preceding each QRS complex, a normal PR interval (0.12 to 0.20 seconds), and a normal QRS duration (0.06 to 0.10 seconds).First-Degree AV...
380
Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers01:24

Antiarrhythmic Drugs: Class II Agents as β-Adrenergic Blockers

1.3K
Adrenergic stimulation generally impacts cardiac rate and rhythm. Specifically, stimulation of the β-adrenoceptors triggers an increase in intracellular calcium ion influx and pacemaker currents, which may cause arrhythmias. Catecholamines like adrenaline also demonstrate β2-adrenoceptor-mediated hypokalemia, impacting cardiac action potential and disrupting the normal cardiac rhythm. Class II antiarrhythmic drugs are β-adrenoceptor antagonists or β-blockers, which...
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Related Experiment Video

Updated: Dec 24, 2025

Impact of Intracardiac Neurons on Cardiac Electrophysiology and Arrhythmogenesis in an Ex Vivo Langendorff System
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[Tachyarrhythmia caused by low-dose norepinephrine: a case report].

Yanan Cai1, Jianwei Song1, Yiqing Sun2

  • 1Department of Critical Care Medicine, Shijiazhuang Third Hospital, Shijiazhuang 050000, Hebei, China.

Zhonghua Wei Zhong Bing Ji Jiu Yi Xue
|April 11, 2020
PubMed
Summary

Norepinephrine (norepinephrine) can cause dangerous heart rhythm problems (tachyarrhythmia), even at low doses. This case study shows that stopping norepinephrine can restore normal heart rhythm.

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Area of Science:

  • Critical Care Medicine
  • Cardiology
  • Pharmacology

Background:

  • Norepinephrine (NE) is a vasopressor commonly used to manage hypotension.
  • While NE increases blood pressure, its effect on heart rate can be complex due to baroreceptor reflex.
  • Paradoxical effects, including arrhythmias, are occasionally reported.

Observation:

  • A patient in the intensive care unit (ICU) developed tachyarrhythmia.
  • The patient's heart rate increased with escalating doses of NE.
  • Standard antiarrhythmic treatments were ineffective.

Findings:

  • Electrolyte and thyroid function tests ruled out other causes of arrhythmia.
  • Tapering NE dosage led to a decrease in heart rate.
  • Discontinuation of NE resulted in the restoration of normal sinus rhythm.

Implications:

  • This case highlights a potential link between norepinephrine administration and tachyarrhythmia development.
  • Clinicians should consider NE as a potential cause of unexplained tachyarrhythmias in critically ill patients.
  • Careful dose titration and monitoring of cardiac rhythm during NE therapy are crucial.