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Published on: February 8, 2016
Yeast Mycocins: a great potential for application in health
Bruna L Nascimento1, Mateus F Delabeneta1, Lana Rubia B Rosseto1
1Department of Medical and Pharmaceutical Sciences, Avenida Tancredo Neves 3224 CEP: 85806-470, Cascavel, Paraná, Brazil.
Abstract:
Mycocins have demonstrated inhibition of fungi, bacteria, parasites and viruses, in addition to being studied as epidemiological markers and in the development of vaccines. They are defined as extracellular proteins or glycoproteins with different activities, the main mechanism of action being the inhibition of β-glucan synthesis in the cell wall of sensitive strains. Given the resistance problems created by several microorganisms to agents commonly used in clinical practice, the discovery of new substances with this purpose becomes essential. Mycocins have potential as anti-microbials because they show minimal toxicity and do not present resistance.
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