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Transrectal laparoscopy using flexible endoscopy with a submucosal tunneling method: Porcine survival model
Masao Yoshida1, Mitsuru Esaki2, Tatsunori Satoh1
1Division of Endoscopy, Shizuoka Cancer Center, Shizuoka, Japan.
Summary
Transrectal laparoscopy (TRLS) provides a safe and effective method for peritoneal observation and ascites collection. This novel endoscopic approach demonstrated 100% technical success and 28-day survival in a porcine model, confirming its potential for intraperitoneal examination.
Area of Science:
- Minimally Invasive Surgery
- Gastroenterology
- Surgical Innovation
Background:
- Transrectal laparoscopy (TRLS) is a novel endoscopic technique for peritoneal observation.
- Previous studies established feasibility but lacked sufficient follow-up for safety assessment.
- Limited data exists on TRLS for peritoneal fluid collection.
Purpose of the Study:
- To confirm the safety and efficacy of transrectal laparoscopy (TRLS).
- To evaluate the feasibility of ascites collection during TRLS.
- To assess TRLS in a 28-day porcine survival model.
Main Methods:
- Artificial ascites created in 10 pigs.
- TRLS performed: submucosal tunnel, rectal perforation, endoscopic observation, and mucosal closure.
- Post-procedure antibiotics, 28-day survival, and histological evaluation.
Main Results:
- 100% technical success for insertion, ascites collection, and clip closure.
- Complete visualization of peritoneal spaces without adverse events.
- Median procedure time: 36.3 minutes; 100% survival without infection or peritonitis.
Conclusions:
- Transrectal laparoscopy is safe and effective for ascites collection and intraperitoneal examination.
- The technique demonstrated no adverse events or infections in a porcine model.
- TRLS presents a viable option for intraperitoneal assessment.
