Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Synthetic Biology02:55

Synthetic Biology

5.4K
Synthetic biology is an interdisciplinary science that involves using principles from disciplines such as engineering, molecular biology, cell biology, and systems biology. It involves remodeling existing organisms from nature or constructing completely new synthetic organisms for applications such as protein or enzyme production, bioremediation, value-added macromolecule production, and the addition of desirable traits to crops, to name a few.
Golden rice
Golden rice is a genetically modified...
5.4K
The Synapse02:47

The Synapse

132.2K
Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
132.2K
Integration of Synaptic Events01:28

Integration of Synaptic Events

3.3K
Synaptic integration mainly includes the summation of graded potentials. Graded potentials, regardless of their type, cause subtle alterations in membrane voltage, resulting in either depolarization or hyperpolarization. These incremental changes, when combined or summed, can propel the neuron toward its threshold. Consider, for example, a membrane experiencing a +15 mV shift, causing it to depolarize from -70 mV to -55 mV. In this scenario, graded potentials govern the membrane's ability to...
3.3K
Amplifying Signals via Enzymatic Cascade01:22

Amplifying Signals via Enzymatic Cascade

16.7K
When a ligand binds to a cell-surface receptor, the receptor's intracellular domain changes shape, which may either activate its enzyme function or allow its binding to other molecules. The initial signal is amplified by most signal transduction pathways. This means that a single ligand molecule can activate multiple molecules of a downstream target. Proteins that relay a signal are most commonly phosphorylated at one or more sites, activating or inactivating the protein. Kinases catalyze...
16.7K
Symbiosis00:58

Symbiosis

36.7K
Symbiotic relationships are long-term, close interactions between individuals of different species that affect the distribution and abundance of those species. When a relationship is beneficial to both species, this is called mutualism. When the relationship is beneficial to one species but neither beneficial nor harmful to the other species, this is called commensalism. When one organism is harmed to benefit another, the relationship is known as parasitism. These types of relationships often...
36.7K
Protein Networks02:26

Protein Networks

2.7K
2.7K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

A Framework for a Standard-Enabled FAIR Data Management Workflow for Synthetic Biology.

ACS synthetic biology·2026
Same author

A Decade of SBOL Visual: Growing Adoption of a Diagram Standard for Engineering Biology.

ACS synthetic biology·2025
Same author

The need for adaptability in detection, characterization, and attribution of biosecurity threats.

Nature communications·2024
Same author

Evaluating the Contribution of Model Complexity in Predicting Robustness in Synthetic Genetic Circuits.

ACS synthetic biology·2024
Same author

SeqImprove: Machine-Learning-Assisted Curation of Genetic Circuit Sequence Information.

ACS synthetic biology·2024
Same author

Investigating and Modeling the Factors That Affect Genetic Circuit Performance.

ACS synthetic biology·2023
Same journal

A Multitask Prediction Framework for CircRNAs, Drugs, and Diseases Based on Multi-View Information Integration and Graph Contrastive Learning.

ACS synthetic biology·2026
Same journal

Engineering Modular Cargo Loading Strategies for Carboxysome-Derived Protein Particles.

ACS synthetic biology·2026
Same journal

Suppression of Salmonella Effectors with CRISPRi Controls the Immune Response to Bacterial Therapies.

ACS synthetic biology·2026
Same journal

Rational Design of Linalool Dehydratase-Isomerase Enables Efficient Conversion of Phytol to Neophytadiene.

ACS synthetic biology·2026
Same journal

<i>De Novo</i> Biosynthesis of Polyphyllin V in <i>Nicotiana benthamiana</i> through Pathway Reconstruction and UDP-Sugar Engineering.

ACS synthetic biology·2026
Same journal

Rapid and Continuous Directed Evolution in <i>Vibrio natriegens</i> Utilizing an <i>In Vivo</i> Hypermutation System.

ACS synthetic biology·2026
See all related articles

Related Experiment Video

Updated: Dec 24, 2025

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
09:10

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

9.9K

Extending SynBioHub's Functionality with Plugins.

Jeanet Mante1, Zach Zundel1,2, Chris Myers1,2,3

  • 1Department of Biomedical Engineering, University of Utah, Salt Lake City, Utah 84112, United States.

ACS Synthetic Biology
|April 11, 2020
PubMed
Summary
This summary is machine-generated.

SynBioHub now supports more synthetic biology workflows through a new plugin interface. This expansion enables easier data submission, visualization, and download of genetic designs.

More Related Videos

Sealable Femtoliter Chamber Arrays for Cell-free Biology
13:44

Sealable Femtoliter Chamber Arrays for Cell-free Biology

Published on: March 11, 2015

9.8K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.6K

Related Experiment Videos

Last Updated: Dec 24, 2025

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes
09:10

A Fast and Quantitative Method for Post-translational Modification and Variant Enabled Mapping of Peptides to Genomes

Published on: May 22, 2018

9.9K
Sealable Femtoliter Chamber Arrays for Cell-free Biology
13:44

Sealable Femtoliter Chamber Arrays for Cell-free Biology

Published on: March 11, 2015

9.8K
Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms
10:41

Leveraging CyVerse Resources for De Novo Comparative Transcriptomics of Underserved Non-model Organisms

Published on: May 9, 2017

9.6K

Area of Science:

  • Synthetic Biology
  • Bioinformatics
  • Computational Biology

Background:

  • SynBioHub is a central repository for synthetic genetic designs using the Synthetic Biology Open Language (SBOL).
  • Expanding SynBioHub's data processing capabilities is crucial for its integration into diverse synthetic biology workflows.

Purpose of the Study:

  • To develop a flexible plugin interface for SynBioHub to enhance its data processing functionalities.
  • To demonstrate the utility of the plugin interface through the development of diverse example plugins.

Main Methods:

  • A plugin interface was developed for SynBioHub, supporting data submission, visualization, and download functionalities.
  • Three distinct plugins were created as proof-of-concept: SnapGene file submission, genetic part visualization, and plasmid map preparation for download.

Main Results:

  • The developed plugin interface successfully extended SynBioHub's capabilities.
  • Example plugins demonstrated seamless integration for data submission (SnapGene), visualization (genetic parts), and download (plasmid maps).

Conclusions:

  • The new plugin interface significantly enhances SynBioHub's versatility and integration potential within synthetic biology research.
  • This framework facilitates broader adoption and application of SynBioHub in various computational and experimental workflows.