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Updated: Dec 24, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
Published on: March 21, 2025
Use of multiparametric magnetic resonance imaging (mpMRI) in localized prostate cancer
Luke O'Connor1, Alex Wang1, Stephanie M Walker2
1Urologic Oncology Branch, NCI, NIH, Bethesda, MD, USA.
Abstract:
Introduction: Prostate magnetic resonance imaging (MRI) is commonly used for localized disease mainly to detect intraprostatic lesions and to guide biopsies. Despite its documented success in clinical practice, limitations still exist for prostate MRI. In this review, we discuss common clinical uses of prostate MRI, its limitations, and potential solutions for those limitations.Areas covered: Current uses of prostate MRI and challenges discussed. Literature search in PubMed was completed using the keywords "prostate MRI, prostate cancer."Expert opinion: Prostate MRI is a useful method for localization, biopsy, and treatment guidance of prostate cancer. Certain limitations of prostate MRI such as false negatives due to spatial resolution and relatively low repeatability between different radiologists can potentially be solved by investing more on education training and artificial intelligence technology.
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