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Related Concept Videos

Imaging Studies IV: Magnetic Resonance Imaging01:27

Imaging Studies IV: Magnetic Resonance Imaging

190
Introduction:Magnetic Resonance Imaging, or MRI, can include a specialized imaging technique of the urinary system known as Magnetic Resonance Urography (MRU). This radiation-free technique uses strong magnetic fields and radio waves to produce detailed images with the help of a computer. MRU is particularly effective for visualizing fluid-filled structures like the kidneys, ureters, and bladder.Applications of MRI in the Genitourinary SystemKidneys and Ureters: MRI detects tumors, cysts,...
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Magnetic Resonance Imaging01:24

Magnetic Resonance Imaging

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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...
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Updated: Dec 24, 2025

A Cognitive Fusion-guided Prostate Biopsy Using Multiparametric Magnetic Resonance Imaging and Transrectal Ultrasound
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MRI-targeted prostate biopsy: key considerations for pathologists.

Jennifer B Gordetsky1,2, Michelle S Hirsch3, Soroush Rais-Bahrami4,5,6

  • 1Department of Pathology, Vanderbilt University Medical Center, Nashville, TN, USA.

Histopathology
|April 12, 2020
PubMed
Summary
This summary is machine-generated.

Pathologists are crucial for accurate MRI-targeted prostate biopsy analysis. Proper specimen handling and reporting of prostate cancer findings by pathologists significantly impact patient management and treatment decisions.

Keywords:
MRIbiopsypathologyprostate cancerreporting

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Area of Science:

  • Pathology
  • Radiology
  • Urology

Background:

  • Prostate multiparametric magnetic resonance imaging (mp-MRI) and MRI-targeted biopsy improve the diagnosis of clinically significant prostate cancer.
  • Current active surveillance guidelines are based on transrectal ultrasound (TRUS) biopsies, not MRI-targeted biopsies.
  • Analysis and reporting of MRI-targeted biopsy cores can alter Gleason score and tumor burden, impacting patient management.

Purpose of the Study:

  • To discuss the pathologist's role in MRI-targeted prostate biopsy.
  • To focus on specimen processing, pathological findings reporting, and quality assurance for MRI-targeted biopsy programs.
  • To review current issues and literature relevant to pathologists in MRI-targeted prostate biopsy.

Main Methods:

  • Literature search on PubMed using terms: 'prostate cancer', 'pathology', 'histology', 'reporting', 'cores', 'imaging', 'MRI', 'mpMRI'.
  • Focus on original investigations related to MRI-targeted prostate biopsy.
  • Discussion of pathologist's role in specimen processing, reporting, and quality assurance.

Main Results:

  • Pathologists play a vital role in reporting MRI-targeted prostate biopsies.
  • Accurate reporting of grade and extent of prostate cancer influences patient management.
  • Pathologist involvement in quality assurance is essential for successful MRI-targeted biopsy programs.

Conclusions:

  • Pathologists are integral to the success of MRI-targeted prostate biopsy programs.
  • Standardized reporting and quality assurance by pathologists are critical for accurate diagnosis and patient management.
  • The pathologist's role extends to ensuring the reliability of diagnostic information derived from MRI-targeted biopsies.