Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Association of Free Testosterone and DHEA-S with Dyslipidemia in Women with Polycystic Ovarian Syndrome- a case-control study.

EJIFCC·2026
Same author

Corrigendum to "Fabrication of PCL/PVP Electrospun Fibers loaded with Trans-anethole for Bone Regeneration in vitro" [Colloids Surf. B Biointerfaces 171 (2018) 698-706].

Colloids and surfaces. B, Biointerfaces·2026
Same author

Evaluation of chrysin incorporated chitosan-based scaffold for bone regeneration in rat models.

Journal of Indian Society of Periodontology·2025
Same author

Letter to the editor: A preliminary exploration of surgical strategies for solitary papillary thyroid carcinoma on the isthmus.

Oral oncology·2025
Same author

Letter to the editor "The use of 3D computer-aided design to optimize photoimmunotherapy catheter placement".

Oral oncology·2025
Same author

Retraction Note: Letter to the Editor: "Efficacy of subthalamic deep brain stimulation programming strategies for gait disorders in Parkinson's disease: A systematic review and meta-analysis".

Neurosurgical review·2025
Same journal

Development of a device useful to reproducibly produce large quantities of viable and uniform stem cell spheroids with controlled diameters.

Materials science & engineering. C, Materials for biological applications·2022
Same journal

Osteogenic and anti-inflammatory potential of oligochitosan nanoparticles in treating osteomyelitis.

Materials science & engineering. C, Materials for biological applications·2022
Same journal

Enhancing the bioactivity of melt electrowritten PLLA scaffold by convenient, green, and effective hydrophilic surface modification.

Materials science & engineering. C, Materials for biological applications·2022
Same journal

Optimal structural and physical properties of aerogels for promoting robust neurite extension in vitro.

Materials science & engineering. C, Materials for biological applications·2022
Same journal

Effect of recombinant BMP-2 and erythropoietin on osteogenic properties of biomimetic PLA/PCL/HA and PHB/HA scaffolds in critical-size cranial defects model.

Materials science & engineering. C, Materials for biological applications·2022
Same journal

A loofah-inspired scaffold with enhanced mimicking mechanics and tumor cells distribution for in vitro tumor cell culture platform.

Materials science & engineering. C, Materials for biological applications·2022
See all related articles

Related Experiment Video

Updated: Dec 24, 2025

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

12.3K

Temperature- and pH-responsive chitosan-based injectable hydrogels for bone tissue engineering.

K Lavanya1, S Viji Chandran1, K Balagangadharan1

  • 1Department of Biotechnology, School of Bioengineering, SRM Institute of Science and Technology, Kattankulathur 603 203, Tamil Nadu, India.

Materials Science & Engineering. C, Materials for Biological Applications
|April 14, 2020
PubMed
Summary
This summary is machine-generated.

Thermo/pH-responsive chitosan hydrogels show promise for bone tissue engineering (BTE). These injectable materials offer advantages over traditional bone grafts, enhancing repair for bone defects.

Keywords:
Bone defectBone tissue engineeringChitosanThermo/pH-responsive hydrogels

More Related Videos

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.7K
Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.8K

Related Experiment Videos

Last Updated: Dec 24, 2025

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering
12:22

Synthesis of Thermogelling PolyN-isopropylacrylamide-graft-chondroitin Sulfate Composites with Alginate Microparticles for Tissue Engineering

Published on: October 26, 2016

12.3K
Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture
08:05

Preparation of Chitosan-based Injectable Hydrogels and Its Application in 3D Cell Culture

Published on: September 29, 2017

19.7K
Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications
05:26

Fabrication of Size-Controlled and Emulsion-Free Chitosan-Genipin Microgels for Tissue Engineering Applications

Published on: April 13, 2022

3.8K

Area of Science:

  • Biomaterials Science
  • Regenerative Medicine
  • Tissue Engineering

Background:

  • Bone defects often require external intervention for effective repair and regeneration.
  • Bone tissue engineering (BTE) presents advanced alternatives to conventional bone grafting methods.
  • Hydrogels mimic the natural extracellular matrix, making them suitable scaffolds for BTE.

Purpose of the Study:

  • To review the physicochemical properties and applications of thermo/pH-responsive chitosan-based hydrogels.
  • To explore the potential of these hydrogels in bone tissue engineering.
  • To outline future perspectives for chitosan hydrogels in BTE.

Main Methods:

  • Review of existing literature on chitosan hydrogels for BTE.
  • Analysis of thermo/pH-responsive properties of chitosan-based formulations.
  • Evaluation of injectable hydrogel characteristics for bone defect applications.

Main Results:

  • Chitosan (CS) is a natural biopolymer increasingly utilized in BTE.
  • Thermo/pH-responsive CS-based injectable hydrogels exhibit high water absorption, minimal invasiveness, and adaptability to irregular defects.
  • These hydrogels offer promising properties as scaffolds for enhanced bone regeneration.

Conclusions:

  • Thermo/pH-responsive chitosan hydrogels are advantageous materials for bone tissue engineering.
  • Their injectable nature and ability to conform to defect sites facilitate minimally invasive treatment.
  • Further research into CS-based hydrogels holds significant potential for advancing bone regeneration therapies.