Clinical Characteristics and Surgical Safety in Congenital Cataract Eyes with Three Pathological Types of Posterior
Xixia Ding1,2, Linfeng Xiang1,2, Qianwei Wang1,2
1Eye Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, China.
Insights
Congenital cataracts with posterior capsule abnormalities (persistent fetal vasculature, posterior capsule defect, posterior lenticonus) have similar surgical complication rates to those without abnormalities. Skilled surgical techniques ensure safety in these cases.
Area of Science:
- Ophthalmology
- Pediatric Ophthalmology
- Cataract Surgery
Background:
- Congenital cataracts (CCs) can present with various posterior capsule abnormalities (PCAs).
- Understanding the clinical characteristics and surgical implications of PCAs is crucial for pediatric eye care.
Purpose of the Study:
- To characterize three pathological types of PCAs in CCs: persistent fetal vasculature (PFV), posterior capsule defect (PCD), and posterior lenticonus (PLC).
- To evaluate the surgical safety and complication rates in eyes with CC and PCAs compared to those without.
Main Methods:
- Retrospective review of 367 eyes from 239 children with CC undergoing cataract surgery.
- Detailed analysis of surgical videos and recording of intraoperative and postoperative complications within three months.
Main Results:
- PCAs were present in 35.1% of CC eyes, with PCD being the most common (26.7%), followed by PFV (10.9%) and PLC (5.4%).
- PFV and PCD frequently co-occurred. Surgical complication rates ranged from 0-5.4% and did not differ significantly between eyes with or without PCAs (P > 0.05).
Conclusions:
- PFV, PCD, and PLC are significant findings in CCs, potentially linked by abnormal fetal vasculature attachments.
- Despite the presence of PCAs, severe surgical complications can be avoided with meticulous surgical planning and execution.
- This study highlights the safety of cataract surgery in children with CC and PCAs when performed skillfully.
Purpose:
To observe the clinical characteristics of 3 pathological types of posterior capsule abnormalities (PCAs) in congenital cataracts (CCs) and evaluate the surgical safety in these eyes.
Methods:
This study involved 239 children (367 eyes) with CC who underwent cataract surgery at the Eye Hospital of Wenzhou Medical University. All surgery videos were collected for detailed reviews. Intraoperative and postoperative complications (within 3 months) were all recorded.
Results:
The 3 pathological types of PCAs, namely, persistent fetal vasculature (PFV), posterior capsule defect (PCD), and posterior lenticonus (PLC), presented in 129 (35.1%) CC eyes, while 238 (64.9%) eyes were recorded as CC without PCA. The percentages of PFV, PCD, and PLC were 10.9%, 26.7%, and 5.4% in CC eyes (n = 367), respectively. The most common concomitant of PFV eyes was PCD (42.5%), and PFV was the most frequent (17.3%) one in PCD eyes. PLC was only associated with PFV (15%) and PCD (50%). The occurrence rates of surgical complications ranged from 0 to 5.4%, and no statistical difference was found between the eyes with and without PCA (all P > 0.05).
Conclusions:
PFV, PCD, and PLC play a very important role in the CCs. The effect of fetal vessels in PFV eyes might be an abnormally strong attachment on the posterior capsule, leading to PLC and PCD. Even in PCA patients, severe surgical complication can also be avoided with well-designed and skilled operation. This trial is registered with NCT03905044 at http://ClinicalTrials.gov.
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