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Published on: June 8, 2019
Measure Twice: Promise of Liquid Biopsy in Pediatric High-Grade Gliomas
Matthew S Dietz1, Catherine Z Beach2, Ramon Barajas3,4
1Department of Pediatrics, Oregon Health & Science University, Portland, Oregon.
Purpose:
To review and critique the current state of liquid biopsy in pHGG.
Materials And Methods:
Published literature was reviewed for articles related to liquid biopsy in pediatric glioma and adult glioma with a focus on high-grade gliomas.
Results:
This review discusses the current state of liquid biomarkers of pHGG and their potential applications for liquid biopsy development.
Conclusions:
While nascent, the progress toward identifying circulating analytes of pHGG primes the field of neuro-oncoogy for liquid biopsy development.

