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Published on: September 26, 2018
A 2020 Vision of Hypertension
Bernard M Y Cheung1,2,3, Benjamin Or1, Yue Fei1
1Division of Clinical Pharmacology and Therapeutics, Department of Medicine, The University of Hong Kong, Hong Kong, China.
Insights
Hypertension management differs significantly between age groups. Early identification and lifestyle interventions are key for younger individuals, while older adults often require complex pharmacological treatments.
Area of Science:
- Cardiology
- Gerontology
- Public Health
Background:
- Hypertension is a prevalent chronic condition, particularly in the elderly, due to age-related blood pressure increases.
- Risk factors include genetics, intrauterine growth retardation, prematurity, and childhood obesity.
- Blood pressure control is generally more manageable in younger populations.
Purpose of the Study:
- To highlight the differences in hypertension management between younger and older adults.
- To emphasize the importance of early hypertension detection and intervention.
- To discuss current research into novel blood pressure control methods.
Main Methods:
- Literature review on age-related hypertension prevalence and risk factors.
- Analysis of treatment efficacy and challenges in different age demographics.
- Overview of emerging therapeutic strategies, including denervation.
Main Results:
- Non-pharmacological treatments are more effective in younger individuals.
- Older adults often require multiple antihypertensive medications, facing challenges with adverse effects and compliance.
- Novel approaches like denervation are under investigation for blood pressure control.
Conclusions:
- Hypertension management strategies must be tailored to age-specific needs.
- Early intervention and lifestyle modifications are crucial for long-term blood pressure control.
- Ongoing research aims to improve treatment options for difficult-to-manage hypertension.
Abstract:
Hypertension is a common chronic disease affecting a large section of the general population. Hypertension is highly prevalent in the elderly because blood pressure (BP) rises with age. The risk of developing hypertension increases with predisposing genes, intrauterine growth retardation, prematurity and childhood obesity. BP is easier to control in the young. Non-pharmacological treatment through lifestyle changes, such as weight control and leisure-time physical activity, is more likely to be successful in young people. Hypertension in older adults is more difficult to control, requiring the use of more than one antihypertensive drug. Adverse effects and compliance become problematic. Much research is now directed at novel ways of controlling BP such as denervation. The change in definition of hypertension in the American guideline highlights the need to identify and manage hypertension early, at a stage when it is potentially reversible.
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