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Robertsonian heterozygosity and male sterility
O Gabriel-Robez1, C Ratomponirina, C Cranz
1Faculté de Médicine, Institute d'Embryology, Strasbourg/France.
Andrologia
|November 1, 1988
Abstract:
Meiotic and synaptonemal complex studies using electron microscopy were carried out on infertile man with a 13/14 translocation. Synaptonemal complex analysis showed a typical trivalent with incomplete pairing of the acrocentric elements. The sterilizing effect caused by the failure of synapsis is discussed. This pairing failure has a diagnostic value and a poor prognosis.