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Rheumatic heart disease (RHD) management can be divided into two main strategies: prevention and long-term management.Primary PreventionPrimary prevention focuses on timely diagnosis and management of group A streptococcal pharyngitis to prevent acute rheumatic fever. The most widely used antibiotic for treating this condition is intramuscular benzathine penicillin G.Acute Rheumatic Fever TreatmentThe primary treatment goal for a patient diagnosed with acute rheumatic fever is to suppress the...
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AssessmentA comprehensive assessment is essential in managing a patient with rheumatic heart disease (RHD). Begin with obtaining a detailed medical history, including recent streptococcal infections, a history of rheumatic fever, or previously diagnosed rheumatic heart disease. Assess the patient for symptoms such as fever, chest pain, widespread joint pain (arthralgia), tachycardia, pericardial friction rub, muffled heart sounds, heart murmurs, peripheral edema, subcutaneous nodules, and...
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Rheumatologic Medication Use During Pregnancy.

Emily A Peterson1, Jessica Lynton, Allison Bernard

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Managing chronic rheumatic diseases during pregnancy requires individualized care to protect both mother and baby. This involves careful medication selection and shared decision-making among healthcare providers and patients.

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Area of Science:

  • Rheumatology
  • Obstetrics
  • Pharmacology

Background:

  • Chronic rheumatic diseases frequently affect women of reproductive age.
  • Pregnancy outcomes can be significantly impacted by rheumatic disease activity.
  • Effective management is crucial to prevent joint/organ damage and adverse pregnancy effects.

Purpose of the Study:

  • To review current literature on the use of disease-modifying antirheumatic drugs (DMARDs) and biologics during pregnancy and lactation.
  • To provide healthcare professionals with up-to-date information for managing rheumatic diseases in pregnant patients.

Main Methods:

  • Literature review of current research on DMARDs and biologics in pregnancy.
  • Analysis of medication safety profiles for maternal and fetal toxicity.
  • Emphasis on individualized patient assessment and treatment planning.

Main Results:

  • Individualized assessment is key to controlling disease activity while minimizing medication risks.
  • Shared decision-making among patients and multidisciplinary teams is essential.
  • Careful management can mitigate adverse effects of rheumatic diseases on pregnancy.

Conclusions:

  • Optimal management of rheumatic diseases during pregnancy necessitates a collaborative, patient-centered approach.
  • Evidence-based review of DMARDs and biologics aids in safe and effective treatment strategies.
  • Minimizing maternal and fetal toxicity is paramount in treatment decisions.