Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Oogenesis02:07

Oogenesis

68.6K
In human women, oogenesis produces one mature egg cell or ovum for every precursor cell that enters meiosis. This process differs in two unique ways from the equivalent procedure of spermatogenesis in males. First, meiotic divisions during oogenesis are asymmetric, meaning that a large oocyte (containing most of the cytoplasm) and minor polar body are produced as a result of meiosis I, and again following meiosis II. Since only oocytes will go on to form embryos if fertilized, this unequal...
68.6K
Disorders of the Female Reproductive System01:24

Disorders of the Female Reproductive System

3.8K
The female reproductive system can be affected by several disorders, including Premenstrual Syndrome (PMS), Premenstrual Dysphoric Disorder (PMDD), endometriosis, and various forms of cancer. PMS and PMDD are cyclical conditions that cause physical and emotional distress, with symptoms that include edema, mood swings, and food cravings. PMDD is a more severe form of PMS characterized by increased symptom severity that peaks during the luteal phase and tends to improve or resolve shortly after...
3.8K
Menses Phase01:18

Menses Phase

898
The uterine cycle begins with the menstrual phase, which is considered day one of the cycle and typically lasts about five days. This phase is characterized by the degeneration and shedding of the stratum functionalis, the functional layer of the endometrium.
When fertilization does not occur, the corpus luteum deteriorates, causing a significant drop in the levels of estrogen and progesterone in the body. This hormonal decrease triggers the release of prostaglandins, which cause the uterine...
898
Ovarian Cycle01:27

Ovarian Cycle

3.1K
The menstrual cycle includes a critical component known as the ovarian cycle, which undergoes two main phases each month—the follicular phase and the luteal phase. The follicular phase is variable and averaging around 14 days. Ovulation, triggered by a surge in luteinizing hormone (LH), marks the transition between the two phases. The second phase, the luteal phase, is relatively consistent, lasting approximately 14 days, and is marked by the activity of the corpus luteum. While a cycle...
3.1K
Histology of the Uterus01:19

Histology of the Uterus

3.0K
The uterine wall consists of three histological layers: the perimetrium, myometrium, and endometrium. The outermost perimetrium is a thin, serous membrane connected with the broad ligament on the sides, which helps anchor the uterus in the pelvic cavity. The thickest layer, myometrium, is mainly made up of smooth muscle tissue bundles. Its contractions are vital in facilitating the expulsion of the uterine lining, fetus, and placenta during menstruation and childbirth.
The endometrium is the...
3.0K
Metastasis02:30

Metastasis

6.3K
Metastasis is the spread of cancer cells from the original site to distant locations in the body. Cancer cells can spread via blood vessels (hematogenous) as well as lymph vessels in the body.
Epithelial-to-Mesenchymal Transition
The epithelial-to-mesenchymal transition or EMT is a developmental process commonly observed in wound healing, embryogenesis, and cancer metastasis. EMT is induced by transforming growth factor-beta (TGF-β) or receptor tyrosine kinase (RTK) ligands, which further...
6.3K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Para-Aortic Lymph Node Staging and Oncologic Outcomes in Locally Advanced Cervical Cancer: A Narrative Review.

Cancers·2026
Same author

Optimizing media composition for patient-derived organoids in ovarian cancer: a narrative review.

Chinese clinical oncology·2026
Same author

The Impact of Pathogenic Variants of BRCA1, BRCA2 and Other DNA-Repair Genes on the Survival Benefits Conferred by PARP Inhibitors - Single Center Experience from Quebec.

Journal of obstetrics and gynaecology Canada : JOGC = Journal d'obstetrique et gynecologie du Canada : JOGC·2026
Same author

Robotic vs laparoscopic interval cytoreductive surgery in stage III ovarian cancer: an analysis of the National Cancer Database.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026
Same author

From evidence to practice: national patterns of hyperthermic intra-peritoneal chemotherapy use and survival in advanced ovarian cancer.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society·2026
Same author

Minimally invasive cytoreduction for advanced-stage ovarian cancer-a narrative review.

Gynecology and pelvic medicine·2026

Related Experiment Video

Updated: Dec 24, 2025

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

16.4K

Endometriosis-It is not just benign.

Gabriel Levin1, Claudia Cheng2, Martin Healey2

  • 1Department of Obstetrics and Gynecology, Hadassah-Hebrew University Medical Center, Jerusalem, Israel.

Journal of Gynecology Obstetrics and Human Reproduction
|April 14, 2020
PubMed
Summary

Endometriosis significantly impacts women's lives. Emerging evidence suggests endometriosis may be more invasive than previously thought, challenging its classification as a benign gynecological condition.

Keywords:
CancerEndometriosisLaparoscopy

More Related Videos

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

1.3K
A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice
07:12

A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice

Published on: November 24, 2020

5.8K

Related Experiment Videos

Last Updated: Dec 24, 2025

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity
07:20

Intraoperative Detection of Subtle Endometriosis: A Novel Paradigm for Detection and Treatment of Pelvic Pain Associated with the Loss of Peritoneal Integrity

Published on: December 21, 2012

16.4K
Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility
08:07

Establishment of an Experimental Mouse Model of Endometrioma to Study its Related Infertility

Published on: April 5, 2024

1.3K
A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice
07:12

A Syngeneic Murine Model of Endometriosis using Naturally Cycling Mice

Published on: November 24, 2020

5.8K

Area of Science:

  • Gynecology
  • Oncology
  • Pathology

Background:

  • Endometriosis is a prevalent gynecological condition affecting women's quality of life.
  • Traditionally viewed as benign, recent research indicates potential invasive characteristics.
  • This challenges the established understanding and management of endometriosis.

Purpose of the Study:

  • To critically evaluate the perception of endometriosis as a benign disease.
  • To review current literature on the invasive potential of endometriosis.
  • To address the ongoing scientific debate surrounding endometriosis's nature.

Main Methods:

  • Literature review and synthesis of existing research.
  • Analysis of studies investigating endometriosis invasiveness.
  • Commentary on the clinical and scientific implications.

Main Results:

  • Growing evidence links endometriosis to invasive behaviors.
  • The benign classification of endometriosis is increasingly questioned.
  • This necessitates a re-evaluation of its biological mechanisms.

Conclusions:

  • The traditional view of endometriosis as solely benign requires re-examination.
  • Further research into the invasive aspects of endometriosis is crucial.
  • A revised understanding may impact diagnostic and therapeutic strategies.