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Updated: Dec 24, 2025

Development of Inhibitors of Protein-protein Interactions through REPLACE: Application to the Design and Development Non-ATP Competitive CDK Inhibitors
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A novel class of selective CK2 inhibitors targeting its open hinge conformation

Andrea Dalle Vedove1, Francesca Zonta2, Enrico Zanforlin3

  • 1Department of Cellular, Computational and Integrative Biology - CIBIO, University of Trento, Via Sommarive 9, 38123, Trento, Italy.

European Journal of Medicinal Chemistry
|April 14, 2020
PubMed

Keywords:
Chemical synthesis and structural characterizationEndocellular assay and mechanism of actionProtein kinase CK2X-ray crystallography

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