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Digital Home-Monitoring of Patients after Kidney Transplantation: The MACCS Platform
Published on: April 12, 2021
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Metabolic Disorders with Kidney Transplant
Elizabeth Cohen1, Maria Korah2, Glenda Callender3
1Department of Pharmacy, Yale-New Haven Hospital, New Haven, Connecticut.
Summary
Managing metabolic disorders like diabetes, hyperparathyroidism, and obesity is crucial for kidney transplant success. Optimizing these conditions improves patient outcomes and reduces post-transplant complications.
Area of Science:
- Nephrology
- Endocrinology
- Transplant Surgery
Background:
- Metabolic disorders are common in kidney transplant recipients and impact graft survival.
- Hyperglycemia, secondary hyperparathyroidism, and obesity are prevalent and require careful management.
- These conditions increase risks for cardiovascular complications and affect transplant eligibility.
Purpose of the Study:
- To review the management of diabetes, hyperparathyroidism, and obesity in kidney transplant candidates and recipients.
- To highlight the importance of optimizing metabolic health for improved post-transplant outcomes.
- To discuss current data and challenges in managing these disorders within the transplant population.
Main Methods:
- Literature review of studies on metabolic disorders in kidney transplant patients.
- Analysis of data regarding the prevalence and impact of diabetes, hyperparathyroidism, and obesity.
- Examination of current management strategies and their effectiveness.
Main Results:
- New onset diabetes after transplant affects 7%-30% of patients within the first year.
- Secondary hyperparathyroidism persists in up to 66% of kidney transplant recipients.
- Obesity is the most common metabolic disorder, interacting with other conditions and influencing transplant access.
Conclusions:
- Optimizing metabolic disorders pre- and post-transplant is essential for reducing complications.
- Further research is needed for clear guidelines on managing secondary hyperparathyroidism.
- Addressing metabolic health is critical for successful kidney transplantation and long-term graft function.
Keywords:
Cardiovascular DiseasesChronicDyslipidemiasHyperglycemiaHyperparathyroidismParathyroidectomyRenal InsufficiencyRisk AssessmentSecondarycadaver organ transplantationchronic kidney failurediabetesdiabetes mellitusdiabetic nephropathyend stage kidney diseasehyperparathyroidismkidney transplantationmetabolismobesityorgan transplantparathyroid hormonepediatric nephrologyphosphate binderstransplantation
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