Dizygotic twin from conjoined oocytes: a case report
1Al-Yasmeen Fertility and Gynecology Center, 5 Farid Nada Street, Benha, Qalubyia, 13511, Egypt. Yas.magdi@hotmail.com.
Journal of Assisted Reproduction and Genetics
|April 15, 2020
Summary
This case report details the first successful dizygotic twin delivery following the transfer of conjoined blastocysts derived from conjoined oocytes. It highlights the potential for viable pregnancies from unusual oocyte formations.
Area of Science:
- Reproductive Medicine
- Embryology
- Genetics
Background:
- Binovular follicles with conjoined oocytes are rare and their role in dizygotic twinning is debated.
- Previous reports documented mature conjoined oocytes but lacked evidence of successful dizygotic twin pregnancies.
Observation:
- A 37-year-old female underwent intracytoplasmic sperm injection (ICSI) using a pair of conjoined oocytes.
- The resulting conjoined blastocysts were transferred during an embryo transfer cycle.
Findings:
- A positive pregnancy test was confirmed 15 days post-transfer.
- Ultrasound revealed a dizygotic pregnancy, leading to the birth of healthy twin boys.
Implications:
- This case represents the first documented instance of dizygotic twin delivery from transferred conjoined blastocysts.
- It suggests a more conservative approach to discarding mature oocytes, even those with unusual morphology, given their potential for healthy fetal development.
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