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Related Concept Videos

Imaging Studies I: Kidney, Ureter, and Bladder Studies01:28

Imaging Studies I: Kidney, Ureter, and Bladder Studies

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Kidney, Ureter, and Bladder (KUB) StudiesKidney, Ureter, and Bladder (KUB) studies are standard diagnostic imaging procedures used to assess the anatomy of the urinary system. They are commonly utilized for patients experiencing abdominal pain or urinary symptoms. By using a simple X-ray of the abdomen, KUB studies can reveal structural and pathological abnormalities within the kidneys, ureters, and bladder. These studies are particularly valuable in diagnosing kidney stones, urinary...
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Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations01:26

Urinary Tract Calculi II: Pathophysiology and Clinical Manifestations

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Renal calculi, commonly termed kidney stones, are crystalline solid masses that form in the kidneys but can occur at any point within the urinary system, encompassing the kidneys, ureters, bladder, and urethra.The pathophysiology of renal stones involves several key factors: supersaturation of the urine with stone-forming constituents, changes in urine pH, a decrease in urine volume, and the presence of substances that promote or inhibit stone formation.Supersaturation of Urine: This is the...
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Nephrons01:10

Nephrons

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The kidneys are intricate organs with millions of working units known as nephrons. Each nephron features two major structures: the renal corpuscle, which facilitates blood plasma filtration, and the renal tubule, which handles the glomerular filtrate. Blood supply is directly linked to the nephrons. The renal corpuscle consists of the glomerulus, a capillary network, and the Bowman's capsule, a double-walled epithelial structure that encases the glomerulus. The filtering of blood plasma...
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Imaging Studies II: Ultrasonography01:24

Imaging Studies II: Ultrasonography

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IntroductionUltrasonography, or renal ultrasound, is a noninvasive medical imaging technique that uses high-frequency sound waves to visualize the kidneys, ureters, bladder, and surrounding tissues.Indications for Urinary System UltrasonographyUrinary system ultrasonography is indicated in various clinical scenarios, such as:Kidney Stones (Urolithiasis): To detect and monitor the size and presence of kidney or urinary tract stones.Hydronephrosis: To assess the dilation of the renal pelvis and...
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Renal Corpuscle01:20

Renal Corpuscle

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The glomerulus and Bowman's capsule are two essential components of the nephron, which is the functional unit of the kidney. These microscopic structures play a critical role in the process of blood filtration to produce urine.
Glomerulus: Structure and Function
The glomerulus is a tiny, intricate network of capillaries located at the beginning of the nephron. It's enveloped by the Bowman's capsule and receives its blood supply from an afferent arteriole, which divides into numerous...
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Imaging Studies VII: Vascular Imaging01:19

Imaging Studies VII: Vascular Imaging

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DefinitionRenal angiography, also known as renal arteriography, is an imaging technique used to obtain a comprehensive view of blood flow and the vascular structure of blood vessels in the kidneys and surrounding areas.PurposeRenal angiography detects blood vessel abnormalities in the kidneys, such as aneurysms, stenosis, thrombosis, vascular tumors, and renal artery stenosis. It evaluates kidney function and guides interventional treatments like angioplasty or stent placement.Pre-Procedure...
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Update on Renal Neoplasms: Clinicopathologic-Radiologic Correlation With Case-Based Examples.

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  • 1Department of Pathology, Massachusetts General Hospital, Harvard Medical School, 55 Fruit St, Warren 831B, Boston, MA 02114.

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|April 15, 2020
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Summary

This article reviews 12 renal neoplasms, including common and new renal cell carcinoma subtypes. Understanding their radiologic and pathologic features is key for accurate diagnosis and treatment of kidney masses.

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epithelioid angiomyolipomametanephric adenomarenal cell carcinomaurothelial carcinoma

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Area of Science:

  • Urologic pathology
  • Radiology of renal masses
  • Oncology

Background:

  • Renal cell carcinoma (RCC) comprises various subtypes with distinct clinicopathologic features.
  • Accurate diagnosis of renal neoplasms relies on integrating imaging and histopathology.
  • The 2016 World Health Organization (WHO) classification introduced new entities for renal tumors.

Purpose of the Study:

  • To correlate clinicopathologic and radiologic findings of 12 renal neoplasms.
  • To illustrate conventional and newer subtypes of renal cell carcinoma.
  • To discuss infrequent renal neoplasms in the differential diagnosis of renal masses.

Main Methods:

  • Case-based review of 12 renal neoplasms.
  • Presentation of radiologic, gross, and histologic images.
  • Correlation of imaging findings with histopathologic diagnoses.

Main Results:

  • Demonstration of diverse renal neoplasms, including common RCC subtypes and novel entities.
  • Inclusion of infrequent tumors that mimic common renal masses.
  • Visual examples of radiologic, gross, and microscopic features.

Conclusions:

  • Familiarity with radiologic and pathologic characteristics is crucial for diagnosing renal cell carcinoma.
  • Correct identification of renal masses aids in appropriate treatment planning.
  • Integrating imaging and pathology improves the management of renal neoplasms.