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Extracorporeal Membrane Oxygenation Support in Children With Hematologic Malignancies in Sweden
Susanna Ranta1,2, Håkan Kalzén3,4, Anna Nilsson1,2
1Childhood Cancer Research Unit, Department of Women's and Children's Health.
Background:
Extracorporeal membrane oxygenation (ECMO) is used in severe respiratory and/or circulatory failure when conventional critical care fails. Studies on patients with hematologic malignancies on ECMO have shown contradictory results; immunosuppression and coagulopathy are relative contraindications to ECMO.
Observations:
This nationwide Swedish retrospective chart review identified 958 children with hematologic malignancies of whom 12 (1.3%) required ECMO support. Eight patients survived ECMO, 7 the total intensive care period, and 6 survived the underlying malignancy.
Conclusions:
ECMO may be considered in children with hematologic malignancy. Short-term and long-term survival, in this limited group, was similar to that of children on ECMO at large.
