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Viral Recombination00:57

Viral Recombination

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Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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Infection01:20

Infection

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When a pathogen enters the body and reproduces, it can cause an infection, damage body cells, and cause illness symptoms that eventually lead to disease. Therefore, its prevention requires breaking the chain of infection.
The chain begins with pathogens: bacteria, viruses, fungi, prions, or parasites such as protozoa helminths. These can be present on the skin as transient or resident flora, or they can be acquired from the environment. Identifying and treating the type of infection and...
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Viral Mutations00:36

Viral Mutations

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A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
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Cross-reactivity00:42

Cross-reactivity

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Overview
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Viruses with RNA Genomes01:29

Viruses with RNA Genomes

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RNA viruses are categorized into positive-strand, negative-strand, or double-stranded groups based on their genomic structure and replication mechanisms. This classification dictates how they exploit host cellular machinery for protein synthesis and replication. Some RNA viruses also utilize reverse transcription as part of their life cycle, further diversifying their replication strategies.Positive-Strand RNA VirusesPositive-strand RNA viruses have genomes that function directly as messenger...
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Diversity of Protists II01:27

Diversity of Protists II

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Alveolates are a group of organisms recognized by the presence of alveoli, which are cytoplasmic sacs located beneath the cell membrane. While their function remains uncertain, alveoli may help regulate water balance by controlling how much water enters and leaves the cell. In dinoflagellates, these structures may serve as armor plates. There are three major types of alveolates: ciliates, which move using cilia; dinoflagellates, which use flagella for movement; and apicomplexans, which are...
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Related Experiment Video

Updated: Dec 24, 2025

Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings
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Author Spotlight: A Cost-Effective Genomic Workflow for Advancing Rabies Control in Resource-Limited Settings

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Animal Reservoirs: Harboring the Next Pandemic.

Myrna E Watanabe

    Bioscience
    |April 15, 2020
    PubMed
    Summary

    Most emerging infectious diseases are zoonoses, originating from domesticated animals and wildlife. Understanding these transmission pathways is crucial for public health and disease prevention strategies.

    Area of Science:

    • Veterinary Medicine
    • Epidemiology
    • Public Health

    Background:

    • Emerging infectious diseases (EIDs) pose a significant threat to global health.
    • A substantial proportion of EIDs are zoonotic in origin, meaning they are transmitted from animals to humans.

    Purpose of the Study:

    • To summarize recent findings on the origins of emerging infectious diseases.
    • To highlight the role of animal-to-human transmission (zoonoses) in the emergence of new diseases.

    Main Methods:

    • Review of recent scientific literature and epidemiological studies.
    • Analysis of data on disease transmission pathways.

    Main Results:

    • The majority of emerging infectious diseases identified in recent studies are zoonoses.

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  • Transmission occurs from both domesticated animals and wildlife populations to humans.
  • Conclusions:

    • Zoonotic spillover from animals is a primary driver of emerging infectious diseases.
    • Continued surveillance and research into animal-human interfaces are essential for mitigating future outbreaks.