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Bioactive paper provides a low-cost platform for diagnostics.

Robert Pelton1

  • 1Department of Chemical Engineering, JHE-136, McMaster University, Hamilton, Ontario, Canada L8S 4L7.

Trends in Analytical Chemistry : TRAC
|April 15, 2020
PubMed
Summary
This summary is machine-generated.

Bioactive paper offers analytical functions for pathogen detection without hardware. This emerging technology has broad societal impacts, from kitchens to disaster relief in developing nations.

Keywords:
AntibodyAntimicrobial paperBacteriophageBioactive paperBiosensorDNA aptamerLateral flowPaper-supported assayPaperfluidicsPathogen detection

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Area of Science:

  • Materials Science
  • Analytical Chemistry
  • Biotechnology

Background:

  • Bioactive paper is a novel class of paper-based materials.
  • These materials can perform analytical functions typically requiring laboratory equipment or electronic devices.
  • Emerging research in bioactive paper is gaining traction globally, with key contributions from Canada, USA, Finland, and Australia.

Purpose of the Study:

  • To review the emerging field of bioactive paper.
  • To highlight the potential of paper-based analytical devices, particularly for pathogen detection.
  • To explore early research exploiting paper's properties for microfluidic applications.

Main Methods:

  • Literature review of bioactive paper research.
  • Focus on paper's material and surface properties.
  • Exclusion of printed electronics and plastic-supported devices.

Main Results:

  • Bioactive paper can serve as a platform for analytical functions.
  • Pathogen detection is a highly promising application for this technology.
  • Paper-based microfluidics (paperfluidics) leverage the porosity of paper.

Conclusions:

  • Bioactive paper represents a significant advancement in portable analytical devices.
  • The simplicity and low-cost nature of paper-based detection offer widespread societal benefits.
  • Further research in bioactive paper holds potential for diverse applications, especially in resource-limited settings.