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Development of an Electrochemical DNA Biosensor to Detect a Foodborne Pathogen

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Published on: June 3, 2018

Ensuring food safety using aptamer based assays: Electroanalytical approach.

Hedieh Malekzad¹, Abolghasem Jouyban^1,2, Mohammad Hasanzadeh³

¹Pharmaceutical Analysis Research Center and Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran.

Trends in Analytical Chemistry : TRAC

|April 15, 2020

Summary

Aptamers are superior receptors for sensitive biosensors. This review highlights electrochemical aptasensors for detecting food contaminants, crucial for human health and safety.

Keywords:

Apta-assay Aptasensor Biosensing Biotechnology Electroanalytical chemistry Food additive Food contamination Food safety Nanoscience and nanotechnology

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Area of Science:

Biotechnology
Analytical Chemistry
Food Science

Background:

Aptamers offer superior affinity and selectivity over traditional biologic receptors for biosensor development.
Electrochemical aptasensors have shown success in biomedical applications.
The food industry requires rapid, sensitive, and economical analytical methods for contaminant detection.

Purpose of the Study:

To review and categorize food hazards.
To summarize recent advancements in electrochemical aptasensors for food contaminant detection.
To highlight the potential of aptasensors in ensuring food safety.

Main Methods:

Literature review of aptamer-based biosensors.
Categorization of food hazards and contaminants.
Summary and analysis of recent electrochemical aptasensor designs and applications in the food sector.
Discussion of assay modifications, including nanomaterials and amplification strategies.

Main Results:

Aptamers, when integrated with electrochemical techniques and assay design, provide highly sensitive detection methods.
Various food contaminants can be effectively detected using electrochemical aptasensors.
Nanomaterials and amplification strategies enhance aptasensor performance for food analysis.

Conclusions:

Electrochemical aptasensors represent a promising technology for addressing food safety concerns.
Further development of these sensors is crucial for rapid and reliable detection of health-threatening food contaminants.
Aptasensor technology can contribute significantly to safeguarding public health through improved food analysis.