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Related Concept Videos

Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

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Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
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Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

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Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
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Asthma-I: Introduction01:29

Asthma-I: Introduction

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Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
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Factors Affecting the Risk of Infection01:26

Factors Affecting the Risk of Infection

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The hosts' susceptibility to infection depends on several factors. The integrity of the skin and mucous membranes helps protect the body against microbial attacks. When the skin is altered, the chance of infection, limb loss, and even death increases.
The integrity and count of the white blood cells help the body resist pathogens and fight infection. When impaired, it reduces the body's resistance to pathogens. The acidic pH levels of the gastrointestinal, genitourinary tracts, and skin...
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Allergic Reactions02:06

Allergic Reactions

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Overview
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Autoimmune Disorders01:29

Autoimmune Disorders

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Autoimmune diseases are a group of disorders in which the body's immune system mistakenly attacks its own cells, tissues, and organs. This results from an overactive immune response against substances and tissues normally present in the body. Let's delve into the concept and mechanism of autoimmune diseases from an immune system point of view, explore different causes and examples of such diseases, and discuss potential solutions.
Concept and Mechanism of Autoimmune Diseases
The immune...
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Revue medicale de Liege·2020
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[Viral infections and asthma].

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Misplaced mid-septal infarction aggravating sub aortic obstruction in hypertrophic obstructive cardiomyopathy.

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Related Experiment Video

Updated: Dec 24, 2025

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
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Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

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[Atopy and infections].

M Radermecker1

  • 1Service de Pneumologie-Allergologie, CHU de Liège, 4000 LIÈGE, Belgique.

Revue Francaise D'Allergologie Et D'Immunologie Clinique
|April 15, 2020
PubMed
Summary
This summary is machine-generated.

Atopy and infections have a reciprocal relationship, where each condition can worsen the other. Managing allergic inflammation and addressing infections are key to treating atopic diseases like asthma.

Keywords:
AsthmaAsthmeAtopieAtopyInfectionsVirus

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Assessment of Lymphocyte Migration in an Ex Vivo Transmigration System
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Advanced Imaging of Lung Homing Human Lymphocytes in an Experimental In Vivo Model of Allergic Inflammation Based on Light-sheet Microscopy
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Area of Science:

  • Immunology
  • Allergology
  • Infectious Diseases

Context:

  • Atopy, characterized by allergic inflammation, creates a predisposition to infections in affected organs.
  • Conversely, infections can exacerbate atopic conditions by amplifying inflammatory responses and increasing organ hyperreactivity.

Purpose:

  • To explore the bidirectional relationship between atopy and infections.
  • To discuss the implications for managing atopic diseases, including asthma.

Summary:

  • Atopic inflammation facilitates infections, necessitating environmental control and anti-inflammatory treatments.
  • Infections worsen atopy by superimposed inflammation and hyperreactivity.
  • Chlamydia pneumoniae infections may play a role in severe asthma, suggesting macrolide use.

Impact:

  • Highlights the importance of a dual approach to managing atopic diseases, addressing both allergic and infectious components.
  • Suggests potential therapeutic strategies, including macrolides for asthma linked to Chlamydia pneumoniae infections.