Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Immunocompetence01:22

Development of Immunocompetence

669
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
669
Vaccinations01:51

Vaccinations

50.9K
Overview
50.9K
Immunological Memory01:23

Immunological Memory

14.7K
Immunological memory, a pivotal pillar of the adaptive immune system, is responsible for the body's ability to remember and respond more swiftly and effectively to previously encountered pathogens. This remarkable feature is what makes vaccines so effective in preventing diseases.
What is Immunological Memory?
Immunological memory is an integral function of the immune system that allows it to recognize and react more rapidly and effectively to pathogens previously encountered. This feature...
14.7K
Transmission-based Precautions I: Contact, Enteric, and Droplets01:17

Transmission-based Precautions I: Contact, Enteric, and Droplets

4.4K
Transmission-based precautions are for patients known to be infected or suspected to be infected or colonized with organisms that pose a significant risk to others. Some transmission-based precautions include contact, enteric, and droplet.
Contact Precautions:
Contact precautions are the measures taken to prevent the transmission of infectious agents, especially epidemiologically important microorganisms such as MRSA or influenza, primarily transmitted through direct or indirect contact with an...
4.4K
Cytotoxic T Cells-mediated Immune Response01:27

Cytotoxic T Cells-mediated Immune Response

6.3K
Cytotoxic T cells are a vital component of the immune system. They have the remarkable ability to identify and target antigens on infected or abnormal cells. These antigens often originate from intracellular pathogens such as viruses or abnormal proteins cancer cells produce.
Immunological surveillance is the ability of immune cells to monitor and eliminate infected cells with intracellular pathogens, neoplastically transformed cells, and cells with non-self antigens. Cytotoxic T cells and NK...
6.3K
Transduction01:16

Transduction

965
Among the three main modes of HGT—transformation, conjugation, and transduction—transduction is unique in that it is mediated by bacteriophages, or bacterial viruses.Transduction occurs in two ways. Generalized transduction occurs during the lytic cycle of a bacteriophage infection. In this process, bacteriophages infect bacterial cells, replicate within them, and ultimately cause cell lysis, releasing newly assembled virions. Occasionally, random fragments of the bacterial genome...
965

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Establishing a high sensitivity detection method for SARS-CoV-2 IgM/IgG and developing a clinical application of this method.

Emerging microbes & infections·2020
Same author

Reactivity of aromatic contaminants towards nitrate radical in tropospheric gas and aqueous phase.

Journal of hazardous materials·2020
Same author

Dysregulated adaptive immune response contributes to severe COVID-19.

Cell research·2020
Same author

Theoretical investigation on the contribution of HO, SO<sub>4</sub><sup>-</sup> and CO<sub>3</sub><sup>-</sup> radicals to the degradation of phenacetin in water: Mechanisms, kinetics, and toxicity evaluation.

Ecotoxicology and environmental safety·2020
Same author

Identification of Sulfenylated Cysteines in <i>Arabidopsis thaliana</i> Proteins Using a Disulfide-Linked Peptide Reporter.

Frontiers in plant science·2020
Same author

A feasibility study of individual 3D-printed navigation template for the deep external fixator pin position on the iliac crest.

BMC musculoskeletal disorders·2020
Same journal

Perspectives of Electrically generated spin currents in ferromagnetic materials.

Physics letters. A·2024
Same journal

Real time monitoring of the evolution of an epidemic regarded as a physical relaxation process.

Physics letters. A·2020
Same journal

The effect of adaptive behavior on risk propagation in industrial symbiosis networks.

Physics letters. A·2020
Same journal

Locating multiple information sources in social networks based on the naming game.

Physics letters. A·2020
Same journal

Stability of the spreading in small-world network with predictive controller.

Physics letters. A·2020
Same journal

Dynamical response of multi-patch, flux-based models to the input of infected people: Epidemic response to initiated events.

Physics letters. A·2020
See all related articles

Related Experiment Video

Updated: Dec 24, 2025

Intra-lymph Node Injection of Biodegradable Polymer Particles
09:06

Intra-lymph Node Injection of Biodegradable Polymer Particles

Published on: January 2, 2014

15.0K

Immunization strategy based on the critical node in percolation transition.

Yang Liu1, Bo Wei2, Zhen Wang3

  • 1School of Computer and Information Science, Southwest University, Chongqing 400715, China.

Physics Letters. A
|April 15, 2020
PubMed
Summary
This summary is machine-generated.

We developed a novel targeted immunization strategy using percolation theory to control epidemics. This method identifies critical nodes, significantly reducing the number of required immunizations compared to existing strategies.

Keywords:
Critical nodesDegree thresholdImmunization strategyPercolation transition

More Related Videos

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination
11:07

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination

Published on: April 29, 2015

13.6K
Murine Model of Epicutaneously-Induced Immunomodulation
09:06

Murine Model of Epicutaneously-Induced Immunomodulation

Published on: June 24, 2025

356

Related Experiment Videos

Last Updated: Dec 24, 2025

Intra-lymph Node Injection of Biodegradable Polymer Particles
09:06

Intra-lymph Node Injection of Biodegradable Polymer Particles

Published on: January 2, 2014

15.0K
Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination
11:07

Whole-animal Imaging and Flow Cytometric Techniques for Analysis of Antigen-specific CD8+ T Cell Responses after Nanoparticle Vaccination

Published on: April 29, 2015

13.6K
Murine Model of Epicutaneously-Induced Immunomodulation
09:06

Murine Model of Epicutaneously-Induced Immunomodulation

Published on: June 24, 2025

356

Area of Science:

  • Network Science
  • Epidemiology
  • Statistical Physics

Background:

  • Controlling epidemic spread with limited resources is a significant challenge.
  • Effective immunization strategies are crucial for public health and network management.

Purpose of the Study:

  • To propose a novel targeted immunization strategy based on percolation transition.
  • To enhance epidemic control efficiency by identifying critical nodes for immunization.

Main Methods:

  • The strategy identifies critical nodes by monitoring the disappearance of the maximal second-largest connected component.
  • This approach leverages percolation transition phenomena in network analysis.
  • Experiments were conducted on various artificial and real-world networks.

Main Results:

  • The proposed percolation-based strategy significantly outperforms degree centrality, betweenness centrality, and adaptive degree centrality methods.
  • Achieved 18% to 50% fewer immunizations for equivalent epidemic control.
  • Demonstrated superior efficiency in resource allocation for immunization.

Conclusions:

  • The novel targeted immunization strategy offers a more efficient approach to epidemic control.
  • Identifying critical nodes via percolation transition is a viable method for optimizing immunization campaigns.
  • This strategy provides a valuable tool for resource-constrained public health interventions.