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Related Concept Videos

Viral Recombination00:57

Viral Recombination

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Cells are sometimes infected by more than one virus at once. When two viruses disassemble to expose their genomes for replication in the same cell, similar regions of their genomes can pair together and exchange sequences in a process called recombination. Alternatively, viruses with segmented genomes can swap segments in a process called reassortment.
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Viral Mutations00:36

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A mutation is a change in the sequence of bases of DNA or RNA in a genome. Some mutations occur during replication of the genome due to errors made by the polymerase enzymes that replicate DNA or RNA. Unlike DNA polymerase, RNA polymerase is prone to errors because it is not capable of “proofreading” its work. Viruses with RNA-based genomes, like HIV, therefore accrue mutations faster than viruses with DNA-based genomes. Because mutation and recombination provide the raw material...
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Related Experiment Video

Updated: Dec 24, 2025

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
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[Human hantavirus infections].

N Schöffel1, M Braun1, M H K Bendels1

  • 1Institut für Arbeitsmedizin, Sozialmedizin und Umweltmedizin, Goethe-Universität Frankfurt, Theodor-Stern-Kai 7, 60590 Frankfurt am Main, Deutschland.

Zentralblatt Fur Arbeitsmedizin, Arbeitsschutz Und Ergonomie
|April 15, 2020
PubMed
Summary
This summary is machine-generated.

Hantaviruses, emerging zoonotic diseases, can cause severe illness like hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) in humans. This review covers global epidemiology, pathology, diagnostics, therapy, and prevention for these rodent-borne infections.

Keywords:
BunyaviridaeEmerging diseaseHanta virusInfectious diseaseVirus infection

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Area of Science:

  • Virology: Classification of hantaviruses within the Bunyaviridae family.
  • Zoonotic Diseases: Focus on emerging infectious diseases transmitted from animals to humans.

Context:

  • Hantaviruses are globally distributed, with subtypes specific to certain hosts.
  • Human infection occurs through contact with infected rodent excreta (urine, saliva, feces).
  • Significant occupational health risks exist for agricultural, veterinary, and forestry workers.

Purpose:

  • To provide a comprehensive review of current worldwide knowledge on hantavirus infections in humans.
  • To consolidate information on epidemiology, pathology, diagnostics, therapy, and prevention.

Summary:

  • Hantavirus infections represent a significant global zoonotic threat, causing severe diseases such as HFRS and HCPS.
  • The review details the host-specific geographical distribution and transmission routes of various hantavirus subtypes.
  • Key aspects of disease management, including diagnosis, treatment, and preventative measures, are discussed.

Impact:

  • Enhances understanding of a critical emerging zoonotic disease with worldwide implications.
  • Provides essential information for healthcare professionals, public health officials, and occupational safety experts.
  • Aims to improve the prevention and management strategies for hantavirus infections globally.