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Related Experiment Video

Updated: Dec 24, 2025

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

A Murine Model of Dengue Virus-induced Acute Viral Encephalitis-like Disease

Published on: April 28, 2019

Non-linear Dynamics of Two-Patch Model Incorporating Secondary Dengue Infection.

Arti Mishra¹, Sunita Gakkhar¹

¹Department of Mathematics, Indian Institute of Technology Roorkee, Roorkee, Uttarakhand India.

International Journal of Applied and Computational Mathematics

|April 15, 2020

Summary

This summary is machine-generated.

Human migration significantly impacts dengue epidemics. Migrants can introduce different dengue serotypes, increasing disease spread and severity, as seen in Brazil.

Keywords:

Basic reproduction number Dengue Estimation Human migration Secondary infection Stability

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Protocol for Dengue Infections in Mosquitoes A. aegypti and Infection Phenotype Determination

Protocol for Dengue Infections in Mosquitoes A. aegypti and Infection Phenotype Determination

Published on: July 4, 2007

Area of Science:

Epidemiology
Mathematical Modeling
Infectious Disease Dynamics

Background:

Dengue fever is a significant global health concern.
Human migration patterns can influence the spread of infectious diseases.
Understanding the interplay between migration and dengue is crucial for public health interventions.

Purpose of the Study:

To investigate the impact of human migration on dengue epidemic dynamics.
To analyze how migration affects disease transmission in a multi-patch model.
To evaluate the role of different dengue serotypes in migration-driven outbreaks.

Main Methods:

Developed a vector-host model with two patches, each with a distinct dengue serotype.
Incorporated constant migration rates for susceptible and recovered individuals between patches.
Computed and analyzed the basic reproduction number (R0) concerning migration parameters.
Performed stability analysis of equilibrium states and sensitivity analysis of R0.

Main Results:

Immigration into a patch increases its basic reproduction number, while emigration decreases it.
Migration dynamics significantly influence the overall dengue epidemic's trajectory.
Model simulations and analysis of Brazilian states indicate migration's role in severe outbreaks.

Conclusions:

Human migration is a critical factor in shaping dengue epidemic dynamics and severity.
Migration patterns can exacerbate dengue outbreaks, especially when different serotypes are involved.
The findings highlight the need to integrate migration data into dengue surveillance and control strategies.