Metal complexes driven from Schiff bases and semicarbazones for biomedical and allied applications: a review

M S More1, P G Joshi1, Y K Mishra2,3

  • 1Nanochemistry/QDs R & D Laboratory, Department of Applied Chemistry, Defence Institute of Advanced Technology (DIAT), Ministry of Defence, DRDO, Government of India, Girinagar, Pune, 411025, India.

Keywords:
2,6-DAPBPTSC, 2,6-diacetylpyridine bis-4-phenyl-3-thiosemicarbazone35-DTBP, 3,5-di-tert-butylphenol3CLpro, 3C-like proteaseATNR, Amine terminated liquid natural rubberATT, 2-acetylthiophene thiosemicarbazoneBBPT, Biacetyl bis(4-phenyl-3-thiosemicarbazone)BBTSC, Benzyloxybenzaldehyde thiosemicarbazoneBCG, Bacillus calmette-guérineBDT, BenzyldithiosemicarbazoneBGPT, Bipyridyl glyoxal bis(4-phenyl-3-thiosemicarbazone)BMTS, Biacetyl monothiosemicarbazoneBiological/biomedical activitiesBipy, 2,2-bipyridineCT DNA, Calf thymus deoxyribonucleic acidDAPY, 2,3-diamino-pyridineDTBP, 2,6-di-tert-butylphenolDTBQ, 2,6-di-tert-butyl-4,4′-benzoquinoneEAC, Enrichlish Ascitices CellsHEK-293, Human Embryonic Kidney cellsHL-60, Human leukemia-60 cell lineHeLa, immortal cell linesHepG2, Hepatic cellular carcinoma cells (Human liver cancer cell line)IgG, Immunoglobin GK B HCT-8, Human colon cancer cell lineM-IBDET, N-methylisatin-β-4′,4′-diethylthiosemicarbazoneMCF-7, Michigan Cancer Foundation-7MCF7 cells, Michigan Cancer Foundation-7 (breast cancer cell line)MHV, Mouse hepatitis virusMLV, Moloney leukemia virusMSOPD, N,N-bis(3-methylsalicylidene)-ortho-phenylenediamineMetal complexesNQSC, Naphthoquinone semicarbazoneNQTS, ortho-Naphthoquinone thiosemicarbazoneOLED, Organic light emitting diodePAS, p-amino salicylic acidPPTS, Picolinealdehyde-4-phenyl-3-thiosemicarbazonePhen, 1,10-phenanthrolineSARS CoV, Severe Acute Respiratory Syndrome coronavirusSARS, Severe acute respiratory syndromeSB-HAG, Schiff bases of hydroxyamino guanidinesSK-MEL-30, Human Melanoma Cell LineSK-OV-3 cells, Ovarian cancer cell lineSSB-HAG, salicylaldehyde Schiff bases of HAGSchiff baseSemicarbazoneTCIDw, Tissue culture Infective DoseTTBDQ, 3,5,3′,5′-tetra-tert-butyl-4,4′-diphenoquinoneVSV, vesicular stomatitis virusscCO2, Super-critical carbon dioxide

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