Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Motor-free hip exosuit via high-output fibrous dielectric elastomer actuators.

Science advances·2026
Same author

Phase-specific analysis of 180° turning gait in post-stroke hemiplegia.

Gait & posture·2026
Same author

Optimization of Exoskeleton Assistance Function Based on Physics-Guided Dynamic Fusion Model.

Bioengineering (Basel, Switzerland)·2026
Same author

ClinASO: An open-source platform for rapid drug discovery of gapmer antisense oligonucleotides.

Molecular therapy. Nucleic acids·2026
Same author

A novel variable stiffness actuator with a rotary magnetorheological damper.

The Review of scientific instruments·2026
Same author

Comorbidity-aware transfer learning for neuro-developmental disorder diagnosis.

Neural networks : the official journal of the International Neural Network Society·2026

Related Experiment Video

Updated: Dec 24, 2025

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

14.1K

Standing Air Bubble-Based Micro-Hydraulic Capacitors for Flow Stabilization in Syringe Pump-Driven Systems.

Yidi Zhou1,2, Jixiao Liu1,2,3, Junjia Yan1,2

  • 1School of Mechanical Engineering, Hebei University of Technology, Tianjin 300132, China.

Micromachines
|April 16, 2020
PubMed
Summary

This study introduces a bubble-based hydraulic capacitor to stabilize liquid flow in microfluidic systems. This device significantly reduces flow rate fluctuations from syringe pumps, enabling precise fluid control.

Keywords:
bubble-basedexperimental studiesflow regulationfluidic capacitorstheoretical model

More Related Videos

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications
09:08

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications

Published on: August 30, 2018

12.9K
High Throughput Single-cell and Multiple-cell Micro-encapsulation
16:19

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

19.1K

Related Experiment Videos

Last Updated: Dec 24, 2025

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices
10:22

High Speed Droplet-based Delivery System for Passive Pumping in Microfluidic Devices

Published on: September 2, 2009

14.1K
Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications
09:08

Three-dimensional Printing of Thermoplastic Materials to Create Automated Syringe Pumps with Feedback Control for Microfluidic Applications

Published on: August 30, 2018

12.9K
High Throughput Single-cell and Multiple-cell Micro-encapsulation
16:19

High Throughput Single-cell and Multiple-cell Micro-encapsulation

Published on: June 15, 2012

19.1K

Area of Science:

  • Microfluidics
  • Fluid Dynamics
  • Biomedical Engineering

Background:

  • Syringe pump-driven microfluidic systems often exhibit unstable liquid flow due to motor vibrations, particularly at low flow rates.
  • Precise and stable liquid flow is critical for many microfluidic applications, including diagnostics and drug delivery.

Purpose of the Study:

  • To investigate the physical principles of flow stabilization using a novel bubble-based hydraulic capacitor.
  • To design and validate a cost-efficient system for mitigating flow rate fluctuations in microfluidic devices.

Main Methods:

  • Development of a microfluidic standing air bubble system with tunable micro-bubbles controlled by pneumatic pressure.
  • Theoretical modeling using Euler's law and microfluidic equivalent circuits to analyze the system's behavior.
  • Experimental characterization of flow stabilization performance with varying micro-bubble parameters.

Main Results:

  • The bubble-based hydraulic capacitor effectively stabilizes liquid flow by acting as a hydraulic damper.
  • The system demonstrated a significant reduction in flow pulses, minimizing syringe pump fluctuations by up to 75.3%.
  • A portable system was successfully demonstrated and compared favorably with commercial pressure-driven flow systems.

Conclusions:

  • The bubble-based hydraulic capacitor offers a practical and efficient solution for achieving stable microfluidic flows.
  • This technology enhances the reliability of syringe pump-driven microfluidic systems, broadening their applicability.
  • Further understanding of these bubble-based systems can advance precise fluid handling in microscale applications.