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Published on: April 17, 2012
Rethinking the Role of Radiation Therapy in the Management of Epithelial Ovarian Cancer
Geraldine Jacobson1, Valerie Galvan-Turner2
1Department of Radiation Oncology, West Virginia University, Morgantown WV 26505-9234, USA.
Abstract:
: Radiation has been relegated to a palliative role in the management of epithelial ovarian cancer (EOC). Contemporary radiation techniques, including intensity modulated radiation therapy (IMRT), stereotactic body radiation therapy (SBRT), and image-guided radiation therapy, enable conformal treatment that controls local disease with minimal morbidity. Recent studies from multiple institutions support the role of radiation in the ablative treatment of oligometastatic disease and control of locally recurrent and metastatic disease. Effective local treatment with radiation complements the role of systemic therapy in the management of EOC; reduces symptoms and disease burden, and may contribute to a prolonged drug free interval.
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