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Impact of diabetes as a risk factor in patients undergoing subcutaneous implantable cardioverter defibrillator

Elif Kaya1, Johannes Siebermair1, Nadine Vonderlin1

  • 1Department of Cardiology and Vascular Medicine, West German Heart and Vascular Center, University Hospital Essen, University of Duisburg-Essen, Essen, Germany.

Diabetes & Vascular Disease Research
|April 16, 2020
PubMed

Insights

Patients with diabetes mellitus undergoing subcutaneous implantable cardioverter defibrillator (CIED) surgery did not experience significantly more complications. This study indicates diabetes mellitus is not a major risk factor for adverse events in CIED recipients.

Area of Science:

  • Cardiology
  • Medical Devices
  • Diabetes Management

Background:

  • Patients with diabetes mellitus have higher risks of surgical site infections and perioperative complications.
  • Subcutaneous implantable cardioverter defibrillators (CIEDs) are used for sudden cardiac death prevention, particularly in infection-prone patients.

Purpose of the Study:

  • To evaluate the safety and complication rates of subcutaneous CIED implantation in patients with and without diabetes mellitus.
  • To determine if diabetes mellitus is associated with increased adverse events after subcutaneous CIED procedures.

Main Methods:

  • Retrospective analysis of 48 patients who underwent subcutaneous CIED surgery between February 2016 and May 2019.
  • Evaluation of combined safety endpoints including bleeding, wound problems, infections requiring reoperation, and device malfunction.
  • Comparison of adverse event rates between patients with and without diabetes mellitus.

Main Results:

  • Diabetes mellitus was present in 31.3% of the cohort; these patients were older and had higher BMIs.
  • No significant difference in procedure duration or hospital stay was observed between groups.
  • A trend towards higher adverse event rates in the diabetes mellitus group (20% vs. 12.1%) was noted, but this was not statistically significant (p=0.119).

Conclusions:

  • Diabetes mellitus is a common comorbidity in patients receiving subcutaneous CIEDs.
  • The study suggests that diabetes mellitus is not associated with prolonged hospital stays or a significantly increased rate of periprocedural adverse events following subcutaneous CIED implantation.
Abstract

Keywords:
Subcutaneous implantable cardioverter defibrillatorcomplicationdiabetesoutcome

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