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Ethanol induced skeletal muscle degeneration--role of calcium
J K Baruah1, M Washington, D Kinder
1Department of Neurology, Medical College of Wisconsin, Milwaukee 53226.
Experimental Pathology
|January 1, 1988
Abstract:
The ethanol induced skeletal muscle degeneration is multi-factorial. The morphological changes of the skeletal muscle are more pronounced in the mitochondria. The excessive concentration of calcium in the mitochondria, as shown by the electron-probe micro-analysis, within the first week of ethanol intoxication, even before the appearance of ultrastructural changes suggests that the calcium influx provokes the mitochondrial degeneration.